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http://purl.uniprot.org/citations/21852791http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/21852791http://www.w3.org/2000/01/rdf-schema#comment"The nuclear export of large ribonucleoparticles is complex and requires specific transport factors. Messenger RNAs are exported through the RNA-binding protein Npl3 and the interacting export receptor Mex67. Export of large ribosomal subunits also requires Mex67; however, in this case, Mex67 binds directly to the 5S ribosomal RNA (rRNA) and does not require the Npl3 adaptor. Here, we have discovered a new function of Npl3 in mediating the export of pre-60S ribosomal subunit independently of Mex67. Npl3 interacts with the 25S rRNA, ribosomal and ribosome-associated proteins, as well as with the nuclear pore complex. Mutations in NPL3 lead to export defects of the large subunit and genetic interactions with other pre-60S export factors."xsd:string
http://purl.uniprot.org/citations/21852791http://purl.org/dc/terms/identifier"doi:10.1038/embor.2011.155"xsd:string
http://purl.uniprot.org/citations/21852791http://purl.uniprot.org/core/author"Gross T."xsd:string
http://purl.uniprot.org/citations/21852791http://purl.uniprot.org/core/author"Baierlein C."xsd:string
http://purl.uniprot.org/citations/21852791http://purl.uniprot.org/core/author"Krebber H."xsd:string
http://purl.uniprot.org/citations/21852791http://purl.uniprot.org/core/author"Hackmann A."xsd:string
http://purl.uniprot.org/citations/21852791http://purl.uniprot.org/core/date"2011"xsd:gYear
http://purl.uniprot.org/citations/21852791http://purl.uniprot.org/core/name"EMBO Rep"xsd:string
http://purl.uniprot.org/citations/21852791http://purl.uniprot.org/core/pages"1024-1031"xsd:string
http://purl.uniprot.org/citations/21852791http://purl.uniprot.org/core/title"The mRNA export factor Npl3 mediates the nuclear export of large ribosomal subunits."xsd:string
http://purl.uniprot.org/citations/21852791http://purl.uniprot.org/core/volume"12"xsd:string
http://purl.uniprot.org/citations/21852791http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/21852791
http://purl.uniprot.org/citations/21852791http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/21852791
http://purl.uniprot.org/uniprot/#_Q03862-mappedCitation-21852791http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21852791
http://purl.uniprot.org/uniprot/#_P39705-mappedCitation-21852791http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21852791
http://purl.uniprot.org/uniprot/#_P04456-mappedCitation-21852791http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21852791
http://purl.uniprot.org/uniprot/#_P04147-mappedCitation-21852791http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21852791
http://purl.uniprot.org/uniprot/#_Q02630-mappedCitation-21852791http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21852791
http://purl.uniprot.org/uniprot/#_P20449-mappedCitation-21852791http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21852791
http://purl.uniprot.org/uniprot/#_P38861-mappedCitation-21852791http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21852791
http://purl.uniprot.org/uniprot/#_P38883-mappedCitation-21852791http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21852791
http://purl.uniprot.org/uniprot/#_Q01560-mappedCitation-21852791http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21852791
http://purl.uniprot.org/uniprot/#_Q99257-mappedCitation-21852791http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21852791
http://purl.uniprot.org/uniprot/P20449http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/21852791