http://purl.uniprot.org/citations/21852791 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/21852791 | http://www.w3.org/2000/01/rdf-schema#comment | "The nuclear export of large ribonucleoparticles is complex and requires specific transport factors. Messenger RNAs are exported through the RNA-binding protein Npl3 and the interacting export receptor Mex67. Export of large ribosomal subunits also requires Mex67; however, in this case, Mex67 binds directly to the 5S ribosomal RNA (rRNA) and does not require the Npl3 adaptor. Here, we have discovered a new function of Npl3 in mediating the export of pre-60S ribosomal subunit independently of Mex67. Npl3 interacts with the 25S rRNA, ribosomal and ribosome-associated proteins, as well as with the nuclear pore complex. Mutations in NPL3 lead to export defects of the large subunit and genetic interactions with other pre-60S export factors."xsd:string |
http://purl.uniprot.org/citations/21852791 | http://purl.org/dc/terms/identifier | "doi:10.1038/embor.2011.155"xsd:string |
http://purl.uniprot.org/citations/21852791 | http://purl.uniprot.org/core/author | "Gross T."xsd:string |
http://purl.uniprot.org/citations/21852791 | http://purl.uniprot.org/core/author | "Baierlein C."xsd:string |
http://purl.uniprot.org/citations/21852791 | http://purl.uniprot.org/core/author | "Krebber H."xsd:string |
http://purl.uniprot.org/citations/21852791 | http://purl.uniprot.org/core/author | "Hackmann A."xsd:string |
http://purl.uniprot.org/citations/21852791 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
http://purl.uniprot.org/citations/21852791 | http://purl.uniprot.org/core/name | "EMBO Rep"xsd:string |
http://purl.uniprot.org/citations/21852791 | http://purl.uniprot.org/core/pages | "1024-1031"xsd:string |
http://purl.uniprot.org/citations/21852791 | http://purl.uniprot.org/core/title | "The mRNA export factor Npl3 mediates the nuclear export of large ribosomal subunits."xsd:string |
http://purl.uniprot.org/citations/21852791 | http://purl.uniprot.org/core/volume | "12"xsd:string |
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http://purl.uniprot.org/uniprot/#_P20449-mappedCitation-21852791 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21852791 |
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http://purl.uniprot.org/uniprot/#_P38883-mappedCitation-21852791 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21852791 |
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http://purl.uniprot.org/uniprot/P20449 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/21852791 |