http://purl.uniprot.org/citations/21857973 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/21857973 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/21857973 | http://www.w3.org/2000/01/rdf-schema#comment | "The Drosophila Ten-m (also called Tenascin-major, or odd Oz (odz)) gene has been associated with a pair-rule phenotype. We identified and characterized new alleles of Drosophila Ten-m to establish that this gene is not responsible for segmentation defects but rather causes defects in motor neuron axon routing. In Ten-m mutants the inter-segmental nerve (ISN) often crosses segment boundaries and fasciculates with the ISN in the adjacent segment. Ten-m is expressed in the central nervous system and epidermal stripes during the stages when the growth cones of the neurons that form the ISN navigate to their targets. Over-expression of Ten-m in epidermal cells also leads to ISN misrouting. We also found that Filamin, an actin binding protein, physically interacts with the Ten-m protein. Mutations in cheerio, which encodes Filamin, cause defects in motor neuron axon routing like those of Ten-m. During embryonic development, the expression of Filamin and Ten-m partially overlap in ectodermal cells. These results suggest that Ten-m and Filamin in epidermal cells might together influence growth cone progression."xsd:string |
http://purl.uniprot.org/citations/21857973 | http://purl.org/dc/terms/identifier | "doi:10.1371/journal.pone.0022956"xsd:string |
http://purl.uniprot.org/citations/21857973 | http://purl.org/dc/terms/identifier | "doi:10.1371/journal.pone.0022956"xsd:string |
http://purl.uniprot.org/citations/21857973 | http://purl.uniprot.org/core/author | "Zheng L."xsd:string |
http://purl.uniprot.org/citations/21857973 | http://purl.uniprot.org/core/author | "Zheng L."xsd:string |
http://purl.uniprot.org/citations/21857973 | http://purl.uniprot.org/core/author | "Wides R."xsd:string |
http://purl.uniprot.org/citations/21857973 | http://purl.uniprot.org/core/author | "Wides R."xsd:string |
http://purl.uniprot.org/citations/21857973 | http://purl.uniprot.org/core/author | "Bellen H.J."xsd:string |
http://purl.uniprot.org/citations/21857973 | http://purl.uniprot.org/core/author | "Bellen H.J."xsd:string |
http://purl.uniprot.org/citations/21857973 | http://purl.uniprot.org/core/author | "Justice M.J."xsd:string |
http://purl.uniprot.org/citations/21857973 | http://purl.uniprot.org/core/author | "Justice M.J."xsd:string |
http://purl.uniprot.org/citations/21857973 | http://purl.uniprot.org/core/author | "Avraham Z."xsd:string |
http://purl.uniprot.org/citations/21857973 | http://purl.uniprot.org/core/author | "Avraham Z."xsd:string |
http://purl.uniprot.org/citations/21857973 | http://purl.uniprot.org/core/author | "Freger V."xsd:string |
http://purl.uniprot.org/citations/21857973 | http://purl.uniprot.org/core/author | "Freger V."xsd:string |
http://purl.uniprot.org/citations/21857973 | http://purl.uniprot.org/core/author | "Michelson Y."xsd:string |
http://purl.uniprot.org/citations/21857973 | http://purl.uniprot.org/core/author | "Michelson Y."xsd:string |
http://purl.uniprot.org/citations/21857973 | http://purl.uniprot.org/core/author | "Venken K.J."xsd:string |
http://purl.uniprot.org/citations/21857973 | http://purl.uniprot.org/core/author | "Venken K.J."xsd:string |
http://purl.uniprot.org/citations/21857973 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
http://purl.uniprot.org/citations/21857973 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
http://purl.uniprot.org/citations/21857973 | http://purl.uniprot.org/core/name | "PLoS ONE"xsd:string |
http://purl.uniprot.org/citations/21857973 | http://purl.uniprot.org/core/name | "PLoS ONE"xsd:string |