http://purl.uniprot.org/citations/21888974 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/21888974 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/21888974 | http://www.w3.org/2000/01/rdf-schema#comment | "Cupiennius salei single insulin-like growth factor-binding domain protein (SIBD-1), which exhibits an IGFBP N-terminal domain-like profile, was identified in the hemocytes of the spider C. salei. SIBD-1 was purified by RP-HPLC and the sequence determined by a combination of Edman degradation and 5'-3'-RACE PCR. The peptide (8676.08 Da) is composed of 78 amino acids, contains six intrachain disulphide bridges and carries a modified Thr residue at position 2. SIBD-1 mRNA expression was detected by quantitative real-time PCR mainly in hemocytes, but also in the subesophageal nerve mass and muscle. After infection, the SIBD-1 content in the hemocytes decreases and, simultaneously, the temporal SIBD-1 expression seems to be down-regulated. Two further peptides, SIBD-2 and IGFBP-rP1, also exhibiting IGFBP N-terminal domain variants with unknown functions, were identified on cDNA level in spider hemocytes and venom glands. We conclude that SIBD-1 may play an important role in the immune system of spiders."xsd:string |
http://purl.uniprot.org/citations/21888974 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.ibmb.2011.08.003"xsd:string |
http://purl.uniprot.org/citations/21888974 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.ibmb.2011.08.003"xsd:string |
http://purl.uniprot.org/citations/21888974 | http://purl.uniprot.org/core/author | "Schaller J."xsd:string |
http://purl.uniprot.org/citations/21888974 | http://purl.uniprot.org/core/author | "Schaller J."xsd:string |
http://purl.uniprot.org/citations/21888974 | http://purl.uniprot.org/core/author | "Baumann T."xsd:string |
http://purl.uniprot.org/citations/21888974 | http://purl.uniprot.org/core/author | "Baumann T."xsd:string |
http://purl.uniprot.org/citations/21888974 | http://purl.uniprot.org/core/author | "Kampfer U."xsd:string |
http://purl.uniprot.org/citations/21888974 | http://purl.uniprot.org/core/author | "Kampfer U."xsd:string |
http://purl.uniprot.org/citations/21888974 | http://purl.uniprot.org/core/author | "Kuhn-Nentwig L."xsd:string |
http://purl.uniprot.org/citations/21888974 | http://purl.uniprot.org/core/author | "Kuhn-Nentwig L."xsd:string |
http://purl.uniprot.org/citations/21888974 | http://purl.uniprot.org/core/author | "Nentwig W."xsd:string |
http://purl.uniprot.org/citations/21888974 | http://purl.uniprot.org/core/author | "Nentwig W."xsd:string |
http://purl.uniprot.org/citations/21888974 | http://purl.uniprot.org/core/author | "Schurch S."xsd:string |
http://purl.uniprot.org/citations/21888974 | http://purl.uniprot.org/core/author | "Schurch S."xsd:string |
http://purl.uniprot.org/citations/21888974 | http://purl.uniprot.org/core/author | "Chandru S."xsd:string |
http://purl.uniprot.org/citations/21888974 | http://purl.uniprot.org/core/author | "Chandru S."xsd:string |
http://purl.uniprot.org/citations/21888974 | http://purl.uniprot.org/core/author | "Largiader C.R."xsd:string |
http://purl.uniprot.org/citations/21888974 | http://purl.uniprot.org/core/author | "Largiader C.R."xsd:string |
http://purl.uniprot.org/citations/21888974 | http://purl.uniprot.org/core/author | "Streitberger K."xsd:string |
http://purl.uniprot.org/citations/21888974 | http://purl.uniprot.org/core/author | "Streitberger K."xsd:string |
http://purl.uniprot.org/citations/21888974 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
http://purl.uniprot.org/citations/21888974 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |