| http://purl.uniprot.org/citations/21904047 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/21904047 | http://www.w3.org/2000/01/rdf-schema#comment | "Coccidioides immitis is a pathogenic fungus populating the southwestern United States and is a causative agent of coccidioidomycosis, sometimes referred to as Valley Fever. Although the genome of this fungus has been sequenced, many operons are not properly annotated. Crystal structures are presented for a putative uncharacterized protein that shares sequence similarity with ζ-class glutathione S-transferases (GSTs) in both apo and glutathione-bound forms. The apo structure reveals a nonsymmetric homodimer with each protomer comprising two subdomains: a C-terminal helical domain and an N-terminal thioredoxin-like domain that is common to all GSTs. Half-site binding is observed in the glutathione-bound form. Considerable movement of some components of the active site relative to the glutathione-free form was observed, indicating an induced-fit mechanism for cofactor binding. The sequence homology, structure and half-site occupancy imply that the protein is a ζ-class glutathione S-transferase, a maleylacetoacetate isomerase (MAAI)."xsd:string |
| http://purl.uniprot.org/citations/21904047 | http://purl.org/dc/terms/identifier | "doi:10.1107/s1744309111009493"xsd:string |
| http://purl.uniprot.org/citations/21904047 | http://purl.uniprot.org/core/author | "Abendroth J."xsd:string |
| http://purl.uniprot.org/citations/21904047 | http://purl.uniprot.org/core/author | "Myler P.J."xsd:string |
| http://purl.uniprot.org/citations/21904047 | http://purl.uniprot.org/core/author | "Edwards T.E."xsd:string |
| http://purl.uniprot.org/citations/21904047 | http://purl.uniprot.org/core/author | "Sankaran B."xsd:string |
| http://purl.uniprot.org/citations/21904047 | http://purl.uniprot.org/core/author | "Staker B.L."xsd:string |
| http://purl.uniprot.org/citations/21904047 | http://purl.uniprot.org/core/author | "Stewart L.J."xsd:string |
| http://purl.uniprot.org/citations/21904047 | http://purl.uniprot.org/core/author | "Van Voorhis W.C."xsd:string |
| http://purl.uniprot.org/citations/21904047 | http://purl.uniprot.org/core/author | "Sivam D."xsd:string |
| http://purl.uniprot.org/citations/21904047 | http://purl.uniprot.org/core/author | "Dieterich S.H."xsd:string |
| http://purl.uniprot.org/citations/21904047 | http://purl.uniprot.org/core/author | "Leibly D.J."xsd:string |
| http://purl.uniprot.org/citations/21904047 | http://purl.uniprot.org/core/author | "Bryan C.M."xsd:string |
| http://purl.uniprot.org/citations/21904047 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
| http://purl.uniprot.org/citations/21904047 | http://purl.uniprot.org/core/name | "Acta Crystallogr Sect F Struct Biol Cryst Commun"xsd:string |
| http://purl.uniprot.org/citations/21904047 | http://purl.uniprot.org/core/pages | "1038-1043"xsd:string |
| http://purl.uniprot.org/citations/21904047 | http://purl.uniprot.org/core/title | "Structures of a putative zeta-class glutathione S-transferase from the pathogenic fungus Coccidioides immitis."xsd:string |
| http://purl.uniprot.org/citations/21904047 | http://purl.uniprot.org/core/volume | "67"xsd:string |
| http://purl.uniprot.org/citations/21904047 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/21904047 |
| http://purl.uniprot.org/citations/21904047 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/21904047 |
| http://purl.uniprot.org/uniprot/#_D2YW48-mappedCitation-21904047 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21904047 |
| http://purl.uniprot.org/uniprot/D2YW48 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/21904047 |