| http://purl.uniprot.org/citations/21929573 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/21929573 | http://www.w3.org/2000/01/rdf-schema#comment | "The frequencies of human leukocyte antigen (HLA) class I and class II specificities and haplotypic associations were determined in 1940 unrelated donors from Castilla y León and compared with other Iberian, Mediterranean and European populations. Specificities were determined using polymerase chain reaction reverse sequence-specific oligonucleotide or polymerase chain reaction sequence-specific primer techniques. In the analysis, 19, 29 and 13 specificities were found for HLA-A, -B and -DRB1, respectively, with HLA-A*02 (26%), -A*01 (11%), -B*44 (16%), -B*35 (10%), -DRB1*07 (16%) and -DRB1*13 (14%) showing the highest frequencies. In addition, 10 common HLA-A-B-DRB1 haplotypic associations were observed, A*01-B*08-DRB1*03 (3%) and A*29-B*44-DRB1*07 (3%) being the most frequent ones. These findings indicate that the population of Castilla y León is genetically equidistant from the Portuguese and other Spanish populations and shares a common origin with other Iberian populations, in which European, Mediterranean and North African genetic components are present; this is in agreement with the historical and genetic background of the population. These data contribute to a better understanding of the genetic structure of the Iberian Peninsula and provide a healthy control population from our region that should be useful for the study of disease associations."xsd:string |
| http://purl.uniprot.org/citations/21929573 | http://purl.org/dc/terms/identifier | "doi:10.1111/j.1399-0039.2011.01766.x"xsd:string |
| http://purl.uniprot.org/citations/21929573 | http://purl.uniprot.org/core/author | "Gonzalez M."xsd:string |
| http://purl.uniprot.org/citations/21929573 | http://purl.uniprot.org/core/author | "Santamaria C."xsd:string |
| http://purl.uniprot.org/citations/21929573 | http://purl.uniprot.org/core/author | "San Miguel J.F."xsd:string |
| http://purl.uniprot.org/citations/21929573 | http://purl.uniprot.org/core/author | "Marin L."xsd:string |
| http://purl.uniprot.org/citations/21929573 | http://purl.uniprot.org/core/author | "Corral R."xsd:string |
| http://purl.uniprot.org/citations/21929573 | http://purl.uniprot.org/core/author | "Balanzategui A."xsd:string |
| http://purl.uniprot.org/citations/21929573 | http://purl.uniprot.org/core/author | "Garcia-Sanz R."xsd:string |
| http://purl.uniprot.org/citations/21929573 | http://purl.uniprot.org/core/author | "Chillon M.C."xsd:string |
| http://purl.uniprot.org/citations/21929573 | http://purl.uniprot.org/core/author | "Alcoceba M."xsd:string |
| http://purl.uniprot.org/citations/21929573 | http://purl.uniprot.org/core/author | "Martin-Jimenez P."xsd:string |
| http://purl.uniprot.org/citations/21929573 | http://purl.uniprot.org/core/author | "Sarasquete M.E."xsd:string |
| http://purl.uniprot.org/citations/21929573 | http://purl.uniprot.org/core/author | "Puig N."xsd:string |
| http://purl.uniprot.org/citations/21929573 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
| http://purl.uniprot.org/citations/21929573 | http://purl.uniprot.org/core/name | "Tissue Antigens"xsd:string |
| http://purl.uniprot.org/citations/21929573 | http://purl.uniprot.org/core/pages | "249-255"xsd:string |
| http://purl.uniprot.org/citations/21929573 | http://purl.uniprot.org/core/title | "Frequency of HLA-A, -B and -DRB1 specificities and haplotypic associations in the population of Castilla y Leon (northwest-central Spain)."xsd:string |
| http://purl.uniprot.org/citations/21929573 | http://purl.uniprot.org/core/volume | "78"xsd:string |
| http://purl.uniprot.org/citations/21929573 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/21929573 |
| http://purl.uniprot.org/citations/21929573 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/21929573 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C3H3-mappedCitation-21929573 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21929573 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C3I1-mappedCitation-21929573 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21929573 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C3I5-mappedCitation-21929573 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21929573 |