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http://purl.uniprot.org/citations/21934649 | http://www.w3.org/2000/01/rdf-schema#comment | "FOXA transcription factors are potent, context-specific mediators of development that hold specialized functions in hormone-dependent tissues. Over the last several years, FOXA1 has emerged as a critical mediator of nuclear steroid receptor signalling, manifest at least in part through regulation of androgen receptor and oestrogen receptor activity. Recent findings point towards a major role for FOXA1 in modulating nuclear steroid receptor activity in breast and prostate cancer, and suggest that FOXA1 may significantly contribute to pro-tumourigenic phenotypes. The present review article will focus on the mechanisms, consequence, and clinical relevance of FOXA1-mediated steroid nuclear receptor signalling in human malignancy."xsd:string |
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http://purl.uniprot.org/citations/21934649 | http://purl.uniprot.org/core/author | "Hickey T.E."xsd:string |
http://purl.uniprot.org/citations/21934649 | http://purl.uniprot.org/core/author | "Knudsen K.E."xsd:string |
http://purl.uniprot.org/citations/21934649 | http://purl.uniprot.org/core/author | "Augello M.A."xsd:string |
http://purl.uniprot.org/citations/21934649 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
http://purl.uniprot.org/citations/21934649 | http://purl.uniprot.org/core/name | "EMBO J"xsd:string |
http://purl.uniprot.org/citations/21934649 | http://purl.uniprot.org/core/pages | "3885-3894"xsd:string |
http://purl.uniprot.org/citations/21934649 | http://purl.uniprot.org/core/title | "FOXA1: master of steroid receptor function in cancer."xsd:string |
http://purl.uniprot.org/citations/21934649 | http://purl.uniprot.org/core/volume | "30"xsd:string |
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