| http://purl.uniprot.org/citations/2194290 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2194290 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2194290 | http://www.w3.org/2000/01/rdf-schema#comment | "The human immunodeficiency virus (HIV) tat protein (Tat) is a positive regulator of virus gene expression and replication. Biotinylated Tat was used as a probe to screen a lambda gt11 fusion protein library, and a complementary DNA encoding a protein that interacts with Tat was cloned. Expression of this protein, designated TBP-1 (for Tat binding protein-1), was observed in a variety of cell lines, with expression being highest in human cells. TBP-1 was localized predominantly in the nucleus, which is consistent with the nuclear localization of Tat. In cotransfection experiments, expression of TBP-1 was able to specifically suppress Tat-mediated transactivation. The strategy described may be useful for direct identification and cloning of genes encoding proteins that associate with other proteins to modulate their activity in a positive or negative fashion."xsd:string |
| http://purl.uniprot.org/citations/2194290 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.2194290"xsd:string |
| http://purl.uniprot.org/citations/2194290 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.2194290"xsd:string |
| http://purl.uniprot.org/citations/2194290 | http://purl.uniprot.org/core/author | "Perkins A."xsd:string |
| http://purl.uniprot.org/citations/2194290 | http://purl.uniprot.org/core/author | "Perkins A."xsd:string |
| http://purl.uniprot.org/citations/2194290 | http://purl.uniprot.org/core/author | "Nelbock P."xsd:string |
| http://purl.uniprot.org/citations/2194290 | http://purl.uniprot.org/core/author | "Nelbock P."xsd:string |
| http://purl.uniprot.org/citations/2194290 | http://purl.uniprot.org/core/author | "Rosen C.A."xsd:string |
| http://purl.uniprot.org/citations/2194290 | http://purl.uniprot.org/core/author | "Rosen C.A."xsd:string |
| http://purl.uniprot.org/citations/2194290 | http://purl.uniprot.org/core/author | "Dillion P.J."xsd:string |
| http://purl.uniprot.org/citations/2194290 | http://purl.uniprot.org/core/author | "Dillion P.J."xsd:string |
| http://purl.uniprot.org/citations/2194290 | http://purl.uniprot.org/core/date | "1990"xsd:gYear |
| http://purl.uniprot.org/citations/2194290 | http://purl.uniprot.org/core/date | "1990"xsd:gYear |
| http://purl.uniprot.org/citations/2194290 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/2194290 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/2194290 | http://purl.uniprot.org/core/pages | "1650-1653"xsd:string |
| http://purl.uniprot.org/citations/2194290 | http://purl.uniprot.org/core/pages | "1650-1653"xsd:string |
| http://purl.uniprot.org/citations/2194290 | http://purl.uniprot.org/core/title | "A cDNA for a protein that interacts with the human immunodeficiency virus Tat transactivator."xsd:string |
| http://purl.uniprot.org/citations/2194290 | http://purl.uniprot.org/core/title | "A cDNA for a protein that interacts with the human immunodeficiency virus Tat transactivator."xsd:string |
| http://purl.uniprot.org/citations/2194290 | http://purl.uniprot.org/core/volume | "248"xsd:string |
| http://purl.uniprot.org/citations/2194290 | http://purl.uniprot.org/core/volume | "248"xsd:string |
| http://purl.uniprot.org/citations/2194290 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/2194290 |
| http://purl.uniprot.org/citations/2194290 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/2194290 |