| http://purl.uniprot.org/citations/21947259 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/21947259 | http://www.w3.org/2000/01/rdf-schema#comment | "Although lymphomas account for almost half of blood-derived cancers that are diagnosed each year, the causes of new cases are poorly understood, as reflected by the relatively few risk factors established. Galectin-1, an immunoregulatory ß-galactoside-binding protein, has been widely associated with tumor-immune escape. The aim of the present work was to study the relationship between tumor growth rate, aggressiveness, and response to cyclophosphamide (Cy) therapy with regard to Gal-1 expression in murine T-cell lymphoma models. By means of a disruptive selection process for tumor growth rate, we generated two lymphoma variants from a parental T-cell lymphoma, which have unique characteristics in terms of tumor growth rate, spontaneous regression, metastatic capacity, Gal-1 expression and sensitivity to Cy therapy. Here, we show that Gal-1 expression strongly correlates with tumor growth rate, metastatic capacity and response to single-dose Cy therapy in T-cell lymphoma models; this association might have important consequences for evaluating prognosis and treatments of this type of tumors."xsd:string |
| http://purl.uniprot.org/citations/21947259 | http://purl.org/dc/terms/identifier | "doi:10.1007/s00262-011-1114-3"xsd:string |
| http://purl.uniprot.org/citations/21947259 | http://purl.uniprot.org/core/author | "Rabinovich G.A."xsd:string |
| http://purl.uniprot.org/citations/21947259 | http://purl.uniprot.org/core/author | "Roggero E."xsd:string |
| http://purl.uniprot.org/citations/21947259 | http://purl.uniprot.org/core/author | "Croci D.O."xsd:string |
| http://purl.uniprot.org/citations/21947259 | http://purl.uniprot.org/core/author | "Hess L."xsd:string |
| http://purl.uniprot.org/citations/21947259 | http://purl.uniprot.org/core/author | "Salatino M."xsd:string |
| http://purl.uniprot.org/citations/21947259 | http://purl.uniprot.org/core/author | "Scharovsky O.G."xsd:string |
| http://purl.uniprot.org/citations/21947259 | http://purl.uniprot.org/core/author | "Zacarias Fluck M.F."xsd:string |
| http://purl.uniprot.org/citations/21947259 | http://purl.uniprot.org/core/author | "Di Masso R.J."xsd:string |
| http://purl.uniprot.org/citations/21947259 | http://purl.uniprot.org/core/author | "Stupirski J.C."xsd:string |
| http://purl.uniprot.org/citations/21947259 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
| http://purl.uniprot.org/citations/21947259 | http://purl.uniprot.org/core/name | "Cancer Immunol Immunother"xsd:string |
| http://purl.uniprot.org/citations/21947259 | http://purl.uniprot.org/core/pages | "469-480"xsd:string |
| http://purl.uniprot.org/citations/21947259 | http://purl.uniprot.org/core/title | "The aggressiveness of murine lymphomas selected in vivo by growth rate correlates with galectin-1 expression and response to cyclophosphamide."xsd:string |
| http://purl.uniprot.org/citations/21947259 | http://purl.uniprot.org/core/volume | "61"xsd:string |
| http://purl.uniprot.org/citations/21947259 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/21947259 |
| http://purl.uniprot.org/citations/21947259 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/21947259 |
| http://purl.uniprot.org/uniprot/#_P16045-mappedCitation-21947259 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21947259 |
| http://purl.uniprot.org/uniprot/P16045 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/21947259 |