| http://purl.uniprot.org/citations/21947420 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/21947420 | http://www.w3.org/2000/01/rdf-schema#comment | "Bone size (BS) is one of the major risk factors for osteoporotic fractures. BS variation is genetically determined to a substantial degree with heritability over 50%, but specific genes underlying variation of BS are still largely unknown. To identify specific genes for BS in Chinese, initial genome-wide association scan (GWAS) study and follow-up replication study were performed. In initial GWAS study, a group of 12 contiguous single-nucleotide polymorphism (SNP)s, which span a region of ~25 kb and locate at the upstream of HMGN3 gene (high-mobility group nucleosomal binding domain 3), achieved moderate association signals for spine BS, with P values ranging from 6.2E-05 to 1.8E-06. In the follow-up replication study, eight of the 12 SNPs were detected suggestive replicate associations with BS in 1,728 unrelated female Caucasians, which have well-known differences from Chinese in ethnic genetic background. The SNPs in the region of HMGN3 gene formed a tightly combined haplotype block in both Chinese and Caucasians. The results suggest that the genomic region containing HMGN3 gene may be associated with spine BS in Chinese."xsd:string |
| http://purl.uniprot.org/citations/21947420 | http://purl.org/dc/terms/identifier | "doi:10.1007/s00439-011-1093-7"xsd:string |
| http://purl.uniprot.org/citations/21947420 | http://purl.uniprot.org/core/author | "Guo Y."xsd:string |
| http://purl.uniprot.org/citations/21947420 | http://purl.uniprot.org/core/author | "Li J."xsd:string |
| http://purl.uniprot.org/citations/21947420 | http://purl.uniprot.org/core/author | "Shen H."xsd:string |
| http://purl.uniprot.org/citations/21947420 | http://purl.uniprot.org/core/author | "Xu X.H."xsd:string |
| http://purl.uniprot.org/citations/21947420 | http://purl.uniprot.org/core/author | "Liu Y.J."xsd:string |
| http://purl.uniprot.org/citations/21947420 | http://purl.uniprot.org/core/author | "Tian Q."xsd:string |
| http://purl.uniprot.org/citations/21947420 | http://purl.uniprot.org/core/author | "Liu Y.Z."xsd:string |
| http://purl.uniprot.org/citations/21947420 | http://purl.uniprot.org/core/author | "Yang T.L."xsd:string |
| http://purl.uniprot.org/citations/21947420 | http://purl.uniprot.org/core/author | "Dong S.S."xsd:string |
| http://purl.uniprot.org/citations/21947420 | http://purl.uniprot.org/core/author | "Deng H.W."xsd:string |
| http://purl.uniprot.org/citations/21947420 | http://purl.uniprot.org/core/author | "Deng F.Y."xsd:string |
| http://purl.uniprot.org/citations/21947420 | http://purl.uniprot.org/core/author | "Lei S.F."xsd:string |
| http://purl.uniprot.org/citations/21947420 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
| http://purl.uniprot.org/citations/21947420 | http://purl.uniprot.org/core/name | "Hum Genet"xsd:string |
| http://purl.uniprot.org/citations/21947420 | http://purl.uniprot.org/core/pages | "463-469"xsd:string |
| http://purl.uniprot.org/citations/21947420 | http://purl.uniprot.org/core/title | "Genome-wide association study identifies HMGN3 locus for spine bone size variation in Chinese."xsd:string |
| http://purl.uniprot.org/citations/21947420 | http://purl.uniprot.org/core/volume | "131"xsd:string |
| http://purl.uniprot.org/citations/21947420 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/21947420 |
| http://purl.uniprot.org/citations/21947420 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/21947420 |
| http://purl.uniprot.org/uniprot/#_A0A087WZE9-mappedCitation-21947420 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21947420 |
| http://purl.uniprot.org/uniprot/#_Q15651-mappedCitation-21947420 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21947420 |
| http://purl.uniprot.org/uniprot/#_A0A994J3W4-mappedCitation-21947420 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21947420 |