| http://purl.uniprot.org/citations/21949016 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/21949016 | http://www.w3.org/2000/01/rdf-schema#comment | "Regulatory T cells (Tregs) play a critical role in the immune system to regulate peripheral tolerance and prevent autoimmunity. However, the relative importance of different mechanisms of Treg function remains obscure. In this article, we reveal a limited role for programmed cell death pathways in mediating Treg suppression of conventional T cells. We show that Tregs are able to suppress the proliferation of conventional T cells that are resistant to apoptosis (Bim(-/-), Bim(-/-)Puma(-/-), Bcl-2 transgenic) or receptor-interacting serine-threonine kinase-dependent necrosis (also referred to as regulated necrosis or necroptosis) (Ripk3(-/-)) in several in vitro and in vivo assays. These data suggest that programmed cell death pathways, such as apoptosis and receptor-interacting serine-threonine kinase-dependent necrosis, are not required for Treg-mediated suppression."xsd:string |
| http://purl.uniprot.org/citations/21949016 | http://purl.org/dc/terms/identifier | "doi:10.4049/jimmunol.1100548"xsd:string |
| http://purl.uniprot.org/citations/21949016 | http://purl.uniprot.org/core/author | "Vignali D.A."xsd:string |
| http://purl.uniprot.org/citations/21949016 | http://purl.uniprot.org/core/author | "Green D.R."xsd:string |
| http://purl.uniprot.org/citations/21949016 | http://purl.uniprot.org/core/author | "Delgoffe G.M."xsd:string |
| http://purl.uniprot.org/citations/21949016 | http://purl.uniprot.org/core/author | "Szymczak-Workman A.L."xsd:string |
| http://purl.uniprot.org/citations/21949016 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
| http://purl.uniprot.org/citations/21949016 | http://purl.uniprot.org/core/name | "J Immunol"xsd:string |
| http://purl.uniprot.org/citations/21949016 | http://purl.uniprot.org/core/pages | "4416-4420"xsd:string |
| http://purl.uniprot.org/citations/21949016 | http://purl.uniprot.org/core/title | "Cutting edge: regulatory T cells do not mediate suppression via programmed cell death pathways."xsd:string |
| http://purl.uniprot.org/citations/21949016 | http://purl.uniprot.org/core/volume | "187"xsd:string |
| http://purl.uniprot.org/citations/21949016 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/21949016 |
| http://purl.uniprot.org/citations/21949016 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/21949016 |
| http://purl.uniprot.org/uniprot/#_A0A1L4AQQ4-mappedCitation-21949016 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21949016 |
| http://purl.uniprot.org/uniprot/#_D3Z2M5-mappedCitation-21949016 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21949016 |
| http://purl.uniprot.org/uniprot/#_E9PZP3-mappedCitation-21949016 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21949016 |
| http://purl.uniprot.org/uniprot/#_P10415-mappedCitation-21949016 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21949016 |
| http://purl.uniprot.org/uniprot/#_A0A1B0GR88-mappedCitation-21949016 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21949016 |
| http://purl.uniprot.org/uniprot/#_A0A1L4AQQ5-mappedCitation-21949016 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21949016 |
| http://purl.uniprot.org/uniprot/#_A0A1L4AQQ8-mappedCitation-21949016 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21949016 |
| http://purl.uniprot.org/uniprot/#_A0A1L4AQR6-mappedCitation-21949016 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21949016 |
| http://purl.uniprot.org/uniprot/#_A0A2I3BPT3-mappedCitation-21949016 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21949016 |
| http://purl.uniprot.org/uniprot/#_A0A7I2V3S7-mappedCitation-21949016 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21949016 |
| http://purl.uniprot.org/uniprot/#_A0A2I3BQW9-mappedCitation-21949016 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21949016 |