RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/21953935http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/21953935http://www.w3.org/2000/01/rdf-schema#comment"Uch37 is a de-ubiquitylating enzyme that is functionally linked with the 26S proteasome via Rpn13, and is essential for metazoan development. Here, we report the X-ray crystal structure of full-length human Uch37 at 2.95 Å resolution. Uch37's catalytic domain is similar to those of all UCH enzymes characterized to date. The C-terminal extension is elongated, predominantly helical and contains coiled coil interactions. Additionally, we provide an initial characterization of Uch37's oligomeric state and identify a systematic error in previous analyses of Uch37 activity. Taken together, these data provide a strong foundation for further analysis of Uch37's several functions."xsd:string
http://purl.uniprot.org/citations/21953935http://purl.org/dc/terms/identifier"doi:10.1002/prot.23147"xsd:string
http://purl.uniprot.org/citations/21953935http://purl.uniprot.org/core/author"Bingman C.A."xsd:string
http://purl.uniprot.org/citations/21953935http://purl.uniprot.org/core/author"Phillips G.N. Jr."xsd:string
http://purl.uniprot.org/citations/21953935http://purl.uniprot.org/core/author"Burgie S.E."xsd:string
http://purl.uniprot.org/citations/21953935http://purl.uniprot.org/core/author"Soni A.B."xsd:string
http://purl.uniprot.org/citations/21953935http://purl.uniprot.org/core/date"2012"xsd:gYear
http://purl.uniprot.org/citations/21953935http://purl.uniprot.org/core/name"Proteins"xsd:string
http://purl.uniprot.org/citations/21953935http://purl.uniprot.org/core/pages"649-654"xsd:string
http://purl.uniprot.org/citations/21953935http://purl.uniprot.org/core/title"Structural characterization of human Uch37."xsd:string
http://purl.uniprot.org/citations/21953935http://purl.uniprot.org/core/volume"80"xsd:string
http://purl.uniprot.org/citations/21953935http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/21953935
http://purl.uniprot.org/citations/21953935http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/21953935
http://purl.uniprot.org/uniprot/#_B4DKB3-mappedCitation-21953935http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21953935
http://purl.uniprot.org/uniprot/#_B2RB07-mappedCitation-21953935http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21953935
http://purl.uniprot.org/uniprot/#_B4DW59-mappedCitation-21953935http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21953935
http://purl.uniprot.org/uniprot/#_B7Z9U9-mappedCitation-21953935http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21953935
http://purl.uniprot.org/uniprot/#_Q9Y5K5-mappedCitation-21953935http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21953935
http://purl.uniprot.org/uniprot/Q9Y5K5http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/21953935
http://purl.uniprot.org/uniprot/B2RB07http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/21953935
http://purl.uniprot.org/uniprot/B4DW59http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/21953935
http://purl.uniprot.org/uniprot/B7Z9U9http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/21953935
http://purl.uniprot.org/uniprot/B4DKB3http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/21953935