| http://purl.uniprot.org/citations/21964024 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/21964024 | http://www.w3.org/2000/01/rdf-schema#comment | "Dysregulation of the T cell-dependent Ab response can lead to numerous immunological disorders, ranging from systemic lupus erythematosus to B cell lymphomas. Cellular processes governed by MHC class II proteins play a major role in this response and its dysregulation. The extent to which processes controlled by the diverse family of MHC class I proteins impact such autoimmune and neoplastic disorders, however, is less clear. In this study, we genetically dissect the contributions of individual MHC class I family members and the pathological processes under their control in the systemic lupus erythematosus-like disease of BXSB.Yaa mice and B cell lymphomagenesis of SJL mice. This study reveals a powerful repressive regulatory axis comprised of MHC class I-dependent CD8(+) T cells and NK cells. These results indicate that the predominant role of the MHC class I protein family in such immunological disorders is to protect from more aggressive diseases."xsd:string |
| http://purl.uniprot.org/citations/21964024 | http://purl.org/dc/terms/identifier | "doi:10.4049/jimmunol.1101776"xsd:string |
| http://purl.uniprot.org/citations/21964024 | http://purl.uniprot.org/core/author | "Roopenian D.C."xsd:string |
| http://purl.uniprot.org/citations/21964024 | http://purl.uniprot.org/core/author | "Shin D.M."xsd:string |
| http://purl.uniprot.org/citations/21964024 | http://purl.uniprot.org/core/author | "Morse H.C."xsd:string |
| http://purl.uniprot.org/citations/21964024 | http://purl.uniprot.org/core/author | "Sproule T.J."xsd:string |
| http://purl.uniprot.org/citations/21964024 | http://purl.uniprot.org/core/author | "Schott W.H."xsd:string |
| http://purl.uniprot.org/citations/21964024 | http://purl.uniprot.org/core/author | "Bubier J.A."xsd:string |
| http://purl.uniprot.org/citations/21964024 | http://purl.uniprot.org/core/author | "Avenesyan L."xsd:string |
| http://purl.uniprot.org/citations/21964024 | http://purl.uniprot.org/core/author | "McPhee C.G."xsd:string |
| http://purl.uniprot.org/citations/21964024 | http://purl.uniprot.org/core/author | "Steinbuck M.P."xsd:string |
| http://purl.uniprot.org/citations/21964024 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
| http://purl.uniprot.org/citations/21964024 | http://purl.uniprot.org/core/name | "J Immunol"xsd:string |
| http://purl.uniprot.org/citations/21964024 | http://purl.uniprot.org/core/pages | "4695-4704"xsd:string |
| http://purl.uniprot.org/citations/21964024 | http://purl.uniprot.org/core/title | "MHC class I family proteins retard systemic lupus erythematosus autoimmunity and B cell lymphomagenesis."xsd:string |
| http://purl.uniprot.org/citations/21964024 | http://purl.uniprot.org/core/volume | "187"xsd:string |
| http://purl.uniprot.org/citations/21964024 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/21964024 |
| http://purl.uniprot.org/citations/21964024 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/21964024 |
| http://purl.uniprot.org/uniprot/#_A0A0B4J1G3-mappedCitation-21964024 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21964024 |
| http://purl.uniprot.org/uniprot/#_A0A0U1RP02-mappedCitation-21964024 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21964024 |
| http://purl.uniprot.org/uniprot/#_A0A068BER1-mappedCitation-21964024 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21964024 |
| http://purl.uniprot.org/uniprot/#_A0A1B0GQZ2-mappedCitation-21964024 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21964024 |
| http://purl.uniprot.org/uniprot/#_A0A1B0GQZ8-mappedCitation-21964024 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21964024 |
| http://purl.uniprot.org/uniprot/#_A0A0R4J090-mappedCitation-21964024 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21964024 |