| http://purl.uniprot.org/citations/21983562 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
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| http://purl.uniprot.org/citations/21983562 | http://www.w3.org/2000/01/rdf-schema#comment | "Intracellular transport is vital for the function, survival and architecture of every eukaryotic cell. Long-range transport in animal cells is thought to depend exclusively on microtubule tracks. This study reveals an unexpected actin-dependent but microtubule-independent mechanism for long-range transport of vesicles. Vesicles organize their own actin tracks by recruiting the actin nucleation factors Spire1, Spire2 and Formin-2, which assemble an extensive actin network from the vesicles' surfaces. The network connects the vesicles with one another and with the plasma membrane. Vesicles move directionally along these connections in a myosin-Vb-dependent manner to converge and to reach the cell surface. The overall outward-directed movement of the vesicle-actin network is driven by recruitment of vesicles to the plasma membrane in the periphery of the oocyte. Being organized in a dynamic vesicle-actin network allows vesicles to move in a local random manner and a global directed manner at the same time: they can reach any position in the cytoplasm, but also move directionally to the cell surface as a collective. Thus, collective movement within a network is a powerful and flexible mode of vesicle transport."xsd:string |
| http://purl.uniprot.org/citations/21983562 | http://purl.org/dc/terms/identifier | "doi:10.1038/ncb2353"xsd:string |
| http://purl.uniprot.org/citations/21983562 | http://purl.org/dc/terms/identifier | "doi:10.1038/ncb2353"xsd:string |
| http://purl.uniprot.org/citations/21983562 | http://purl.uniprot.org/core/author | "Schuh M."xsd:string |
| http://purl.uniprot.org/citations/21983562 | http://purl.uniprot.org/core/author | "Schuh M."xsd:string |
| http://purl.uniprot.org/citations/21983562 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
| http://purl.uniprot.org/citations/21983562 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
| http://purl.uniprot.org/citations/21983562 | http://purl.uniprot.org/core/name | "Nat. Cell Biol."xsd:string |
| http://purl.uniprot.org/citations/21983562 | http://purl.uniprot.org/core/name | "Nat. Cell Biol."xsd:string |
| http://purl.uniprot.org/citations/21983562 | http://purl.uniprot.org/core/pages | "1431-1436"xsd:string |
| http://purl.uniprot.org/citations/21983562 | http://purl.uniprot.org/core/pages | "1431-1436"xsd:string |
| http://purl.uniprot.org/citations/21983562 | http://purl.uniprot.org/core/title | "An actin-dependent mechanism for long-range vesicle transport."xsd:string |
| http://purl.uniprot.org/citations/21983562 | http://purl.uniprot.org/core/title | "An actin-dependent mechanism for long-range vesicle transport."xsd:string |
| http://purl.uniprot.org/citations/21983562 | http://purl.uniprot.org/core/volume | "13"xsd:string |
| http://purl.uniprot.org/citations/21983562 | http://purl.uniprot.org/core/volume | "13"xsd:string |
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| http://purl.uniprot.org/citations/21983562 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/21983562 |
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| http://purl.uniprot.org/citations/21983562 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/21983562 |
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