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http://purl.uniprot.org/citations/22002768 | http://www.w3.org/2000/01/rdf-schema#comment | "The reduction in synaptic transmission and plasticity in mice lacking the hippocampus-enriched AMPA receptor (AMPAR) auxiliary subunit TARPγ-8 could be a result of a reduction in AMPAR expression or of the direct action of γ-8. We generated TARPγ-8Δ4 knock-in mice lacking the C-terminal PDZ ligand. We found that synaptic transmission and AMPARs were reduced in the mutant mice, but extrasynaptic AMPAR expression and long-term potentiation (LTP) were unaltered. Our findings suggest that there are distinct TARP-dependent mechanisms for synaptic transmission and LTP."xsd:string |
http://purl.uniprot.org/citations/22002768 | http://purl.org/dc/terms/identifier | "doi:10.1038/nn.2952"xsd:string |
http://purl.uniprot.org/citations/22002768 | http://purl.uniprot.org/core/author | "Tomita S."xsd:string |
http://purl.uniprot.org/citations/22002768 | http://purl.uniprot.org/core/author | "Bredt D.S."xsd:string |
http://purl.uniprot.org/citations/22002768 | http://purl.uniprot.org/core/author | "Kato A.S."xsd:string |
http://purl.uniprot.org/citations/22002768 | http://purl.uniprot.org/core/author | "Sumioka A."xsd:string |
http://purl.uniprot.org/citations/22002768 | http://purl.uniprot.org/core/author | "Kauer J.A."xsd:string |
http://purl.uniprot.org/citations/22002768 | http://purl.uniprot.org/core/author | "Brown T.E."xsd:string |
http://purl.uniprot.org/citations/22002768 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
http://purl.uniprot.org/citations/22002768 | http://purl.uniprot.org/core/name | "Nat Neurosci"xsd:string |
http://purl.uniprot.org/citations/22002768 | http://purl.uniprot.org/core/pages | "1410-1412"xsd:string |
http://purl.uniprot.org/citations/22002768 | http://purl.uniprot.org/core/title | "PDZ binding of TARPgamma-8 controls synaptic transmission but not synaptic plasticity."xsd:string |
http://purl.uniprot.org/citations/22002768 | http://purl.uniprot.org/core/volume | "14"xsd:string |
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