| http://purl.uniprot.org/citations/22014523 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/22014523 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/22014523 | http://www.w3.org/2000/01/rdf-schema#comment | "The netrins and slits are two families of widely conserved cues that guide axons and cells along the dorsal-ventral (D-V) axis of animals. These cues typically emanate from the dorsal or ventral midlines and provide spatial information to migrating cells by forming gradients along the D-V axis. Some cell types, however, extend processes to both the dorsal and ventral midlines, suggesting the existence of additional guidance cues that are secreted from both midlines. Here, we report that a previously uncharacterized protein called MADD-4 is secreted by the dorsal and ventral nerve cords of the nematode C. elegans to attract sensory axons and muscle membrane extensions called muscle arms. MADD-4's activity is dependent on UNC-40/DCC, a netrin receptor, which functions cell-autonomously to direct membrane extension. The biological role of MADD-4 orthologs, including ADAMTSL1 and 3 in mammals, is unknown. MADD-4 may therefore represent the founding member of a family of guidance proteins."xsd:string |
| http://purl.uniprot.org/citations/22014523 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.devcel.2011.07.020"xsd:string |
| http://purl.uniprot.org/citations/22014523 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.devcel.2011.07.020"xsd:string |
| http://purl.uniprot.org/citations/22014523 | http://purl.uniprot.org/core/author | "Wong E."xsd:string |
| http://purl.uniprot.org/citations/22014523 | http://purl.uniprot.org/core/author | "Wong E."xsd:string |
| http://purl.uniprot.org/citations/22014523 | http://purl.uniprot.org/core/author | "Selman G."xsd:string |
| http://purl.uniprot.org/citations/22014523 | http://purl.uniprot.org/core/author | "Selman G."xsd:string |
| http://purl.uniprot.org/citations/22014523 | http://purl.uniprot.org/core/author | "Barbier L."xsd:string |
| http://purl.uniprot.org/citations/22014523 | http://purl.uniprot.org/core/author | "Barbier L."xsd:string |
| http://purl.uniprot.org/citations/22014523 | http://purl.uniprot.org/core/author | "D'Souza S.A."xsd:string |
| http://purl.uniprot.org/citations/22014523 | http://purl.uniprot.org/core/author | "D'Souza S.A."xsd:string |
| http://purl.uniprot.org/citations/22014523 | http://purl.uniprot.org/core/author | "Roy P.J."xsd:string |
| http://purl.uniprot.org/citations/22014523 | http://purl.uniprot.org/core/author | "Roy P.J."xsd:string |
| http://purl.uniprot.org/citations/22014523 | http://purl.uniprot.org/core/author | "Seetharaman A."xsd:string |
| http://purl.uniprot.org/citations/22014523 | http://purl.uniprot.org/core/author | "Seetharaman A."xsd:string |
| http://purl.uniprot.org/citations/22014523 | http://purl.uniprot.org/core/author | "Puckrin R."xsd:string |
| http://purl.uniprot.org/citations/22014523 | http://purl.uniprot.org/core/author | "Puckrin R."xsd:string |
| http://purl.uniprot.org/citations/22014523 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
| http://purl.uniprot.org/citations/22014523 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
| http://purl.uniprot.org/citations/22014523 | http://purl.uniprot.org/core/name | "Dev. Cell"xsd:string |
| http://purl.uniprot.org/citations/22014523 | http://purl.uniprot.org/core/name | "Dev. Cell"xsd:string |
| http://purl.uniprot.org/citations/22014523 | http://purl.uniprot.org/core/pages | "669-680"xsd:string |
| http://purl.uniprot.org/citations/22014523 | http://purl.uniprot.org/core/pages | "669-680"xsd:string |