| http://purl.uniprot.org/citations/22033518 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/22033518 | http://www.w3.org/2000/01/rdf-schema#comment | "Innate lymphoid cells (ILC) expressing the transcription factor RORγt induce the postnatal formation of intestinal lymphoid follicles and regulate intestinal homeostasis. RORγt(+) ILC express the aryl hydrocarbon receptor (AhR), a highly conserved, ligand-inducible transcription factor believed to control adaptation of multicellular organisms to environmental challenges. We show that AhR is required for the postnatal expansion of intestinal RORγt(+) ILC and the formation of intestinal lymphoid follicles. AhR activity within RORγt(+) ILC could be induced by dietary ligands such as those contained in vegetables of the family Brassicaceae. AhR-deficient mice were highly susceptible to infection with Citrobacter rodentium, a mouse model for attaching and effacing infections. Our results establish a molecular link between nutrients and the formation of immune system components required to maintain intestinal homeostasis and resistance to infections."xsd:string |
| http://purl.uniprot.org/citations/22033518 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1214914"xsd:string |
| http://purl.uniprot.org/citations/22033518 | http://purl.uniprot.org/core/author | "Esser C."xsd:string |
| http://purl.uniprot.org/citations/22033518 | http://purl.uniprot.org/core/author | "Hobeika E."xsd:string |
| http://purl.uniprot.org/citations/22033518 | http://purl.uniprot.org/core/author | "Vonarbourg C."xsd:string |
| http://purl.uniprot.org/citations/22033518 | http://purl.uniprot.org/core/author | "Diefenbach A."xsd:string |
| http://purl.uniprot.org/citations/22033518 | http://purl.uniprot.org/core/author | "Finke D."xsd:string |
| http://purl.uniprot.org/citations/22033518 | http://purl.uniprot.org/core/author | "Kiss E.A."xsd:string |
| http://purl.uniprot.org/citations/22033518 | http://purl.uniprot.org/core/author | "Kopfmann S."xsd:string |
| http://purl.uniprot.org/citations/22033518 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
| http://purl.uniprot.org/citations/22033518 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/22033518 | http://purl.uniprot.org/core/pages | "1561-1565"xsd:string |
| http://purl.uniprot.org/citations/22033518 | http://purl.uniprot.org/core/title | "Natural aryl hydrocarbon receptor ligands control organogenesis of intestinal lymphoid follicles."xsd:string |
| http://purl.uniprot.org/citations/22033518 | http://purl.uniprot.org/core/volume | "334"xsd:string |
| http://purl.uniprot.org/citations/22033518 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/22033518 |
| http://purl.uniprot.org/citations/22033518 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/22033518 |
| http://purl.uniprot.org/uniprot/#_A0A0B4J1L1-mappedCitation-22033518 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22033518 |
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| http://purl.uniprot.org/uniprot/#_A0A0R4J096-mappedCitation-22033518 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22033518 |
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