| http://purl.uniprot.org/citations/22038715 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/22038715 | http://www.w3.org/2000/01/rdf-schema#comment | "The brains of Alzheimer's disease patients show an increased number of senile plaques compared with normal patients. The major component of the plaques is the β-amyloid peptide, a cleavage product of the amyloid precursor protein (APP). Although the processing of APP has been well-described, the physiological functions of APP and its cleavage products remain unclear. This article reviews the multifunctional roles of an APP orthologue, the C. elegans APL-1. Understanding the function of APL-1 may provide insights into the functions and signaling pathways of human APP. In addition, the physiological effects of introducing human β-amyloid peptide into C. elegans are also reviewed. The C. elegans system provides a powerful genetic model to identify genes regulating the molecular mechanisms underlying intracellular β-amyloid peptide accumulation."xsd:string |
| http://purl.uniprot.org/citations/22038715 | http://purl.org/dc/terms/identifier | "doi:10.1007/s00221-011-2905-7"xsd:string |
| http://purl.uniprot.org/citations/22038715 | http://purl.uniprot.org/core/author | "Li C."xsd:string |
| http://purl.uniprot.org/citations/22038715 | http://purl.uniprot.org/core/author | "Ewald C.Y."xsd:string |
| http://purl.uniprot.org/citations/22038715 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
| http://purl.uniprot.org/citations/22038715 | http://purl.uniprot.org/core/name | "Exp Brain Res"xsd:string |
| http://purl.uniprot.org/citations/22038715 | http://purl.uniprot.org/core/pages | "397-411"xsd:string |
| http://purl.uniprot.org/citations/22038715 | http://purl.uniprot.org/core/title | "Caenorhabditis elegans as a model organism to study APP function."xsd:string |
| http://purl.uniprot.org/citations/22038715 | http://purl.uniprot.org/core/volume | "217"xsd:string |
| http://purl.uniprot.org/citations/22038715 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/22038715 |
| http://purl.uniprot.org/citations/22038715 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/22038715 |
| http://purl.uniprot.org/uniprot/#_Q10651-mappedCitation-22038715 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22038715 |
| http://purl.uniprot.org/uniprot/Q10651 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/22038715 |