| http://purl.uniprot.org/citations/2206531 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2206531 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2206531 | http://www.w3.org/2000/01/rdf-schema#comment | "Voltage-dependent ion channels are thought to consist of a highly conserved repeated core of six transmembrane segments, flanked by more variable cytoplasmic domains. Significant functional differences exist among related types of K+ channels. These differences have been attributed to the variable domains, most prominently the N- and C-termini. We have therefore investigated the functional importance of both termini for the delayed rectifier K+ channel from rat brain encoded by the drk1 gene. This channel has an unusually long C-terminus. Deletions in either terminus affected both activation and inactivation, in some cases profoundly. Unexpectedly, more extensive deletions in both termini restored gating. We could therefore define a core region only slightly longer than the six transmembrane segments that is sufficient for the formation of channels with the kinetics of a delayed rectifier."xsd:string |
| http://purl.uniprot.org/citations/2206531 | http://purl.org/dc/terms/identifier | "doi:10.1016/0896-6273(90)90082-q"xsd:string |
| http://purl.uniprot.org/citations/2206531 | http://purl.org/dc/terms/identifier | "doi:10.1016/0896-6273(90)90082-q"xsd:string |
| http://purl.uniprot.org/citations/2206531 | http://purl.uniprot.org/core/author | "Brown A.M."xsd:string |
| http://purl.uniprot.org/citations/2206531 | http://purl.uniprot.org/core/author | "Brown A.M."xsd:string |
| http://purl.uniprot.org/citations/2206531 | http://purl.uniprot.org/core/author | "Drewe J.A."xsd:string |
| http://purl.uniprot.org/citations/2206531 | http://purl.uniprot.org/core/author | "Drewe J.A."xsd:string |
| http://purl.uniprot.org/citations/2206531 | http://purl.uniprot.org/core/author | "Joho R.H."xsd:string |
| http://purl.uniprot.org/citations/2206531 | http://purl.uniprot.org/core/author | "Joho R.H."xsd:string |
| http://purl.uniprot.org/citations/2206531 | http://purl.uniprot.org/core/author | "Frech G.C."xsd:string |
| http://purl.uniprot.org/citations/2206531 | http://purl.uniprot.org/core/author | "Frech G.C."xsd:string |
| http://purl.uniprot.org/citations/2206531 | http://purl.uniprot.org/core/author | "VanDongen A.M."xsd:string |
| http://purl.uniprot.org/citations/2206531 | http://purl.uniprot.org/core/author | "VanDongen A.M."xsd:string |
| http://purl.uniprot.org/citations/2206531 | http://purl.uniprot.org/core/date | "1990"xsd:gYear |
| http://purl.uniprot.org/citations/2206531 | http://purl.uniprot.org/core/date | "1990"xsd:gYear |
| http://purl.uniprot.org/citations/2206531 | http://purl.uniprot.org/core/name | "Neuron"xsd:string |
| http://purl.uniprot.org/citations/2206531 | http://purl.uniprot.org/core/name | "Neuron"xsd:string |
| http://purl.uniprot.org/citations/2206531 | http://purl.uniprot.org/core/pages | "433-443"xsd:string |
| http://purl.uniprot.org/citations/2206531 | http://purl.uniprot.org/core/pages | "433-443"xsd:string |
| http://purl.uniprot.org/citations/2206531 | http://purl.uniprot.org/core/title | "Alteration and restoration of K+ channel function by deletions at the N- and C-termini."xsd:string |
| http://purl.uniprot.org/citations/2206531 | http://purl.uniprot.org/core/title | "Alteration and restoration of K+ channel function by deletions at the N- and C-termini."xsd:string |
| http://purl.uniprot.org/citations/2206531 | http://purl.uniprot.org/core/volume | "5"xsd:string |
| http://purl.uniprot.org/citations/2206531 | http://purl.uniprot.org/core/volume | "5"xsd:string |