| http://purl.uniprot.org/citations/22100262 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/22100262 | http://www.w3.org/2000/01/rdf-schema#comment | "An effective bidirectional communication between an implantation-competent blastocyst and the receptive uterus is a prerequisite for mammalian reproduction. The blastocyst will implant only when this molecular cross-talk is established. Here we show that the muscle segment homeobox gene (Msh) family members Msx1 and Msx2, which are two highly conserved genes critical for epithelial-mesenchymal interactions during development, also play crucial roles in embryo implantation. Loss of Msx1/Msx2 expression correlates with altered uterine luminal epithelial cell polarity and affects E-cadherin/β-catenin complex formation through the control of Wnt5a expression. Application of Wnt5a in vitro compromised blastocyst invasion and trophoblast outgrowth on cultured uterine epithelial cells. The finding that Msx1/Msx2 genes are critical for conferring uterine receptivity and readiness to implantation could have clinical significance, because compromised uterine receptivity is a major cause of pregnancy failure in IVF programs."xsd:string |
| http://purl.uniprot.org/citations/22100262 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.devcel.2011.09.010"xsd:string |
| http://purl.uniprot.org/citations/22100262 | http://purl.uniprot.org/core/author | "Fujita T."xsd:string |
| http://purl.uniprot.org/citations/22100262 | http://purl.uniprot.org/core/author | "Sun X."xsd:string |
| http://purl.uniprot.org/citations/22100262 | http://purl.uniprot.org/core/author | "Dey S.K."xsd:string |
| http://purl.uniprot.org/citations/22100262 | http://purl.uniprot.org/core/author | "Daikoku T."xsd:string |
| http://purl.uniprot.org/citations/22100262 | http://purl.uniprot.org/core/author | "Xie H."xsd:string |
| http://purl.uniprot.org/citations/22100262 | http://purl.uniprot.org/core/author | "Cha J."xsd:string |
| http://purl.uniprot.org/citations/22100262 | http://purl.uniprot.org/core/author | "Hirota Y."xsd:string |
| http://purl.uniprot.org/citations/22100262 | http://purl.uniprot.org/core/author | "DeMayo F."xsd:string |
| http://purl.uniprot.org/citations/22100262 | http://purl.uniprot.org/core/author | "Maxson R."xsd:string |
| http://purl.uniprot.org/citations/22100262 | http://purl.uniprot.org/core/author | "Lydon J."xsd:string |
| http://purl.uniprot.org/citations/22100262 | http://purl.uniprot.org/core/author | "Tranguch S."xsd:string |
| http://purl.uniprot.org/citations/22100262 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
| http://purl.uniprot.org/citations/22100262 | http://purl.uniprot.org/core/name | "Dev Cell"xsd:string |
| http://purl.uniprot.org/citations/22100262 | http://purl.uniprot.org/core/pages | "1014-1025"xsd:string |
| http://purl.uniprot.org/citations/22100262 | http://purl.uniprot.org/core/title | "Conditional deletion of Msx homeobox genes in the uterus inhibits blastocyst implantation by altering uterine receptivity."xsd:string |
| http://purl.uniprot.org/citations/22100262 | http://purl.uniprot.org/core/volume | "21"xsd:string |
| http://purl.uniprot.org/citations/22100262 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/22100262 |
| http://purl.uniprot.org/citations/22100262 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/22100262 |
| http://purl.uniprot.org/uniprot/#_A0A0G2JDK4-mappedCitation-22100262 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22100262 |
| http://purl.uniprot.org/uniprot/#_A0A0G2JDN0-mappedCitation-22100262 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22100262 |
| http://purl.uniprot.org/uniprot/#_A0A0G2JFX4-mappedCitation-22100262 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22100262 |
| http://purl.uniprot.org/uniprot/#_A0A087WPT2-mappedCitation-22100262 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22100262 |