http://purl.uniprot.org/citations/22119795 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/22119795 | http://www.w3.org/2000/01/rdf-schema#comment | "Subunit 7a of mouse cytochrome c oxidase (Cox) displays a contractile muscle-specific isoform, Cox7a1, that is the major cardiac form. To gain insight into the role of this isoform, we have produced a new knockout mouse line that lacks Cox7a1. We show that homozygous and heterozygous Cox7a1 knockout mice, although viable, have reduced Cox activity and develop a dilated cardiomyopathy at 6 weeks of age. Surprisingly, the cardiomyopathy improves and stabilizes by 6 months of age. Cox7a1 knockout mice incorporate more of the "liver-type" isoform Cox7a2 into the cardiac Cox holoenzyme and, also surprisingly, have higher tissue ATP levels."xsd:string |
http://purl.uniprot.org/citations/22119795 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.mito.2011.11.002"xsd:string |
http://purl.uniprot.org/citations/22119795 | http://purl.uniprot.org/core/author | "Lee M."xsd:string |
http://purl.uniprot.org/citations/22119795 | http://purl.uniprot.org/core/author | "Liu J."xsd:string |
http://purl.uniprot.org/citations/22119795 | http://purl.uniprot.org/core/author | "Lee I."xsd:string |
http://purl.uniprot.org/citations/22119795 | http://purl.uniprot.org/core/author | "Larson D."xsd:string |
http://purl.uniprot.org/citations/22119795 | http://purl.uniprot.org/core/author | "Erickson R.P."xsd:string |
http://purl.uniprot.org/citations/22119795 | http://purl.uniprot.org/core/author | "Pecina P."xsd:string |
http://purl.uniprot.org/citations/22119795 | http://purl.uniprot.org/core/author | "Pecinova A."xsd:string |
http://purl.uniprot.org/citations/22119795 | http://purl.uniprot.org/core/author | "Grossman L.I."xsd:string |
http://purl.uniprot.org/citations/22119795 | http://purl.uniprot.org/core/author | "Huttemann M."xsd:string |
http://purl.uniprot.org/citations/22119795 | http://purl.uniprot.org/core/author | "Doan J.W."xsd:string |
http://purl.uniprot.org/citations/22119795 | http://purl.uniprot.org/core/author | "Maghsoodi B."xsd:string |
http://purl.uniprot.org/citations/22119795 | http://purl.uniprot.org/core/author | "Slack E."xsd:string |
http://purl.uniprot.org/citations/22119795 | http://purl.uniprot.org/core/author | "Klewer S."xsd:string |
http://purl.uniprot.org/citations/22119795 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
http://purl.uniprot.org/citations/22119795 | http://purl.uniprot.org/core/name | "Mitochondrion"xsd:string |
http://purl.uniprot.org/citations/22119795 | http://purl.uniprot.org/core/pages | "294-304"xsd:string |
http://purl.uniprot.org/citations/22119795 | http://purl.uniprot.org/core/title | "Mice deleted for heart-type cytochrome c oxidase subunit 7a1 develop dilated cardiomyopathy."xsd:string |
http://purl.uniprot.org/citations/22119795 | http://purl.uniprot.org/core/volume | "12"xsd:string |
http://purl.uniprot.org/citations/22119795 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/22119795 |
http://purl.uniprot.org/citations/22119795 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/22119795 |
http://purl.uniprot.org/uniprot/#_A0A140LIU4-mappedCitation-22119795 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22119795 |
http://purl.uniprot.org/uniprot/#_Q792A4-mappedCitation-22119795 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22119795 |