http://purl.uniprot.org/citations/22120520 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/22120520 | http://www.w3.org/2000/01/rdf-schema#comment | "Recent anatomical tracing experiments in rodents have established that a subset of mitral cells in the main olfactory bulb (MOB) projects directly to the medial amygdala (MeA), traditionally considered a target of the accessory olfactory bulb. Neurons that project from the MOB to the MeA also show activation in response to conspecific (opposite sex) volatile urine exposure, establishing a direct role of the MOB in semiochemical processing. In addition, olfactory sensory neurons (OSNs) that express the transient receptor potential M5 (TRPM5) channel innervate a subset of glomeruli that respond to putative semiochemical stimuli. In this study, we examined whether the subset of glomeruli targeted by TRPM5-expressing OSNs is innervated by the population of mitral cells that projects to the MeA. We injected the retrograde tracer cholera toxin B (CTB) into the MeA of mice in which the TRPM5 promoter drives green fluorescent protein (GFP). We found overlapping clusters of CTB-labeled mitral cell dendritic branches (CTB(+) ) in TRPM5-GFP(+) glomeruli at significantly greater frequency than expected by chance. Despite the significant degree of colocalization, some amygdalopetal mitral cells extended dendrites to non-TRPM5-GFP glomeruli and vice versa, suggesting that, although significant overlapping glomerular innervation is observed between these two features, it is not absolute."xsd:string |
http://purl.uniprot.org/citations/22120520 | http://purl.org/dc/terms/identifier | "doi:10.1002/cne.23015"xsd:string |
http://purl.uniprot.org/citations/22120520 | http://purl.uniprot.org/core/author | "Thompson J.A."xsd:string |
http://purl.uniprot.org/citations/22120520 | http://purl.uniprot.org/core/author | "Finger T.E."xsd:string |
http://purl.uniprot.org/citations/22120520 | http://purl.uniprot.org/core/author | "Salcedo E."xsd:string |
http://purl.uniprot.org/citations/22120520 | http://purl.uniprot.org/core/author | "Restrepo D."xsd:string |
http://purl.uniprot.org/citations/22120520 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
http://purl.uniprot.org/citations/22120520 | http://purl.uniprot.org/core/name | "J Comp Neurol"xsd:string |
http://purl.uniprot.org/citations/22120520 | http://purl.uniprot.org/core/pages | "1819-1830"xsd:string |
http://purl.uniprot.org/citations/22120520 | http://purl.uniprot.org/core/title | "Second-order input to the medial amygdala from olfactory sensory neurons expressing the transduction channel TRPM5."xsd:string |
http://purl.uniprot.org/citations/22120520 | http://purl.uniprot.org/core/volume | "520"xsd:string |
http://purl.uniprot.org/citations/22120520 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/22120520 |
http://purl.uniprot.org/citations/22120520 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/22120520 |
http://purl.uniprot.org/uniprot/#_Q8BS44-mappedCitation-22120520 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22120520 |
http://purl.uniprot.org/uniprot/#_Q9JJH7-mappedCitation-22120520 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22120520 |
http://purl.uniprot.org/uniprot/Q8BS44 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/22120520 |
http://purl.uniprot.org/uniprot/Q9JJH7 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/22120520 |