| http://purl.uniprot.org/citations/22129199 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/22129199 | http://www.w3.org/2000/01/rdf-schema#comment | "To investigate the biological activity of a novel 24-membered macrolide compound, JBIR-19, isolated from the culture broth of the entomopathogenic fungus Metarhizium sp. fE61, morphological changes in yeast cells were examined using the automated image-processing program CalMorph. Principal components analysis was used to elucidate dynamic changes in the phenotypes, revealing two independent effects of JBIR-19 in yeast cells: bud elongation and increased size of the actin region. Using a fitness assay, we identified the genes required for robust growth in the presence of JBIR-19. Among these were CCW12, YLR111W, and DHH1, which are also involved in abnormal bud morphology. Based on these results and others, we predict intracellular targets of JBIR-19 and its functional interactions."xsd:string |
| http://purl.uniprot.org/citations/22129199 | http://purl.org/dc/terms/identifier | "doi:10.1111/j.1567-1364.2011.00770.x"xsd:string |
| http://purl.uniprot.org/citations/22129199 | http://purl.uniprot.org/core/author | "Kobayashi T."xsd:string |
| http://purl.uniprot.org/citations/22129199 | http://purl.uniprot.org/core/author | "Ogawa H."xsd:string |
| http://purl.uniprot.org/citations/22129199 | http://purl.uniprot.org/core/author | "Ohya Y."xsd:string |
| http://purl.uniprot.org/citations/22129199 | http://purl.uniprot.org/core/author | "Takagi M."xsd:string |
| http://purl.uniprot.org/citations/22129199 | http://purl.uniprot.org/core/author | "Hirata D."xsd:string |
| http://purl.uniprot.org/citations/22129199 | http://purl.uniprot.org/core/author | "Nogami S."xsd:string |
| http://purl.uniprot.org/citations/22129199 | http://purl.uniprot.org/core/author | "Shin-Ya K."xsd:string |
| http://purl.uniprot.org/citations/22129199 | http://purl.uniprot.org/core/author | "Kozone I."xsd:string |
| http://purl.uniprot.org/citations/22129199 | http://purl.uniprot.org/core/author | "Ohnuki S."xsd:string |
| http://purl.uniprot.org/citations/22129199 | http://purl.uniprot.org/core/author | "Ueda J.Y."xsd:string |
| http://purl.uniprot.org/citations/22129199 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
| http://purl.uniprot.org/citations/22129199 | http://purl.uniprot.org/core/name | "FEMS Yeast Res"xsd:string |
| http://purl.uniprot.org/citations/22129199 | http://purl.uniprot.org/core/pages | "293-304"xsd:string |
| http://purl.uniprot.org/citations/22129199 | http://purl.uniprot.org/core/title | "Analysis of the biological activity of a novel 24-membered macrolide JBIR-19 in Saccharomyces cerevisiae by the morphological imaging program CalMorph."xsd:string |
| http://purl.uniprot.org/citations/22129199 | http://purl.uniprot.org/core/volume | "12"xsd:string |
| http://purl.uniprot.org/citations/22129199 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/22129199 |
| http://purl.uniprot.org/citations/22129199 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/22129199 |
| http://purl.uniprot.org/uniprot/#_P39517-mappedCitation-22129199 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22129199 |
| http://purl.uniprot.org/uniprot/#_Q12127-mappedCitation-22129199 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22129199 |
| http://purl.uniprot.org/uniprot/#_Q12528-mappedCitation-22129199 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22129199 |
| http://purl.uniprot.org/uniprot/Q12528 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/22129199 |
| http://purl.uniprot.org/uniprot/P39517 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/22129199 |