| http://purl.uniprot.org/citations/22156524 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/22156524 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/22156524 | http://www.w3.org/2000/01/rdf-schema#comment | "Although O-mannosylated dystroglycan is a receptor for Lassa virus, a causative agent of Lassa fever, recent findings suggest the existence of an alternative receptor(s). Here we identified four molecules as receptors for Lassa virus: Axl and Tyro3, from the TAM family, and dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin (DC-SIGN) and liver and lymph node sinusoidal endothelial calcium-dependent lectin (LSECtin), from the C-type lectin family. These molecules enhanced the binding of Lassa virus to cells and mediated infection independently of dystroglycan. Axl- or Tyro3-mediated infection required intracellular signaling via the tyrosine kinase activity of Axl or Tyro3, whereas DC-SIGN- or LSECtin-mediated infection and binding were dependent on a specific carbohydrate and on ions. The identification of these four molecules as Lassa virus receptors advances our understanding of Lassa virus cell entry."xsd:string |
| http://purl.uniprot.org/citations/22156524 | http://purl.org/dc/terms/identifier | "doi:10.1128/jvi.06451-11"xsd:string |
| http://purl.uniprot.org/citations/22156524 | http://purl.org/dc/terms/identifier | "doi:10.1128/jvi.06451-11"xsd:string |
| http://purl.uniprot.org/citations/22156524 | http://purl.uniprot.org/core/author | "Feldmann H."xsd:string |
| http://purl.uniprot.org/citations/22156524 | http://purl.uniprot.org/core/author | "Feldmann H."xsd:string |
| http://purl.uniprot.org/citations/22156524 | http://purl.uniprot.org/core/author | "Shimojima M."xsd:string |
| http://purl.uniprot.org/citations/22156524 | http://purl.uniprot.org/core/author | "Shimojima M."xsd:string |
| http://purl.uniprot.org/citations/22156524 | http://purl.uniprot.org/core/author | "Stroher U."xsd:string |
| http://purl.uniprot.org/citations/22156524 | http://purl.uniprot.org/core/author | "Stroher U."xsd:string |
| http://purl.uniprot.org/citations/22156524 | http://purl.uniprot.org/core/author | "Ebihara H."xsd:string |
| http://purl.uniprot.org/citations/22156524 | http://purl.uniprot.org/core/author | "Ebihara H."xsd:string |
| http://purl.uniprot.org/citations/22156524 | http://purl.uniprot.org/core/author | "Kawaoka Y."xsd:string |
| http://purl.uniprot.org/citations/22156524 | http://purl.uniprot.org/core/author | "Kawaoka Y."xsd:string |
| http://purl.uniprot.org/citations/22156524 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
| http://purl.uniprot.org/citations/22156524 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
| http://purl.uniprot.org/citations/22156524 | http://purl.uniprot.org/core/name | "J. Virol."xsd:string |
| http://purl.uniprot.org/citations/22156524 | http://purl.uniprot.org/core/name | "J. Virol."xsd:string |
| http://purl.uniprot.org/citations/22156524 | http://purl.uniprot.org/core/pages | "2067-2078"xsd:string |
| http://purl.uniprot.org/citations/22156524 | http://purl.uniprot.org/core/pages | "2067-2078"xsd:string |
| http://purl.uniprot.org/citations/22156524 | http://purl.uniprot.org/core/title | "Identification of cell surface molecules involved in dystroglycan-independent Lassa virus cell entry."xsd:string |
| http://purl.uniprot.org/citations/22156524 | http://purl.uniprot.org/core/title | "Identification of cell surface molecules involved in dystroglycan-independent Lassa virus cell entry."xsd:string |
| http://purl.uniprot.org/citations/22156524 | http://purl.uniprot.org/core/volume | "86"xsd:string |
| http://purl.uniprot.org/citations/22156524 | http://purl.uniprot.org/core/volume | "86"xsd:string |