| http://purl.uniprot.org/citations/2216457 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2216457 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2216457 | http://www.w3.org/2000/01/rdf-schema#comment | "We previously identified a novel protein tyrosine kinase gene, tyk2, by screening a human lymphoid cDNA library with a tyrosine kinase domain specific c-fms restriction fragment under low stringency hybridization conditions. We have now isolated and sequenced a full length tyk2 cDNA clone; demonstrated that this gene is widely expressed in hematopoietic and non-hematopoietic cell lines; and mapped it to chromosome 19p13.2. The cDNA clone is 4176 nucleotides long and codes for a putative protein with a molecular weight of 134 kilodaltons. Hydrophobicity analysis of our sequence does not identify a transmembrane domain, which is found in all members of the receptor class of protein tyrosine kinases; nor can we detect an SH2 domain, found in all previously identified non-receptor protein kinases. We therefore propose that tyk2 is the prototype of a new class of non-receptor protein tyrosine kinases."xsd:string |
| http://purl.uniprot.org/citations/2216457 | http://purl.uniprot.org/core/author | "Shows T."xsd:string |
| http://purl.uniprot.org/citations/2216457 | http://purl.uniprot.org/core/author | "Shows T."xsd:string |
| http://purl.uniprot.org/citations/2216457 | http://purl.uniprot.org/core/author | "Dalla-Favera R."xsd:string |
| http://purl.uniprot.org/citations/2216457 | http://purl.uniprot.org/core/author | "Dalla-Favera R."xsd:string |
| http://purl.uniprot.org/citations/2216457 | http://purl.uniprot.org/core/author | "Byers M."xsd:string |
| http://purl.uniprot.org/citations/2216457 | http://purl.uniprot.org/core/author | "Byers M."xsd:string |
| http://purl.uniprot.org/citations/2216457 | http://purl.uniprot.org/core/author | "Krolewski J.J."xsd:string |
| http://purl.uniprot.org/citations/2216457 | http://purl.uniprot.org/core/author | "Krolewski J.J."xsd:string |
| http://purl.uniprot.org/citations/2216457 | http://purl.uniprot.org/core/author | "Firmbach-Kraft I."xsd:string |
| http://purl.uniprot.org/citations/2216457 | http://purl.uniprot.org/core/author | "Firmbach-Kraft I."xsd:string |
| http://purl.uniprot.org/citations/2216457 | http://purl.uniprot.org/core/date | "1990"xsd:gYear |
| http://purl.uniprot.org/citations/2216457 | http://purl.uniprot.org/core/date | "1990"xsd:gYear |
| http://purl.uniprot.org/citations/2216457 | http://purl.uniprot.org/core/name | "Oncogene"xsd:string |
| http://purl.uniprot.org/citations/2216457 | http://purl.uniprot.org/core/name | "Oncogene"xsd:string |
| http://purl.uniprot.org/citations/2216457 | http://purl.uniprot.org/core/pages | "1329-1336"xsd:string |
| http://purl.uniprot.org/citations/2216457 | http://purl.uniprot.org/core/pages | "1329-1336"xsd:string |
| http://purl.uniprot.org/citations/2216457 | http://purl.uniprot.org/core/title | "TYK2, prototype of a novel class of non-receptor tyrosine kinase genes."xsd:string |
| http://purl.uniprot.org/citations/2216457 | http://purl.uniprot.org/core/title | "TYK2, prototype of a novel class of non-receptor tyrosine kinase genes."xsd:string |
| http://purl.uniprot.org/citations/2216457 | http://purl.uniprot.org/core/volume | "5"xsd:string |
| http://purl.uniprot.org/citations/2216457 | http://purl.uniprot.org/core/volume | "5"xsd:string |
| http://purl.uniprot.org/citations/2216457 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/2216457 |
| http://purl.uniprot.org/citations/2216457 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/2216457 |