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http://purl.uniprot.org/citations/22172991http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/22172991http://www.w3.org/2000/01/rdf-schema#comment"Protein synthesis in mammalian mitochondria produces 13 proteins that are essential subunits of the oxidative phosphorylation complexes. This review provides a detailed outline of each phase of mitochondrial translation including initiation, elongation, termination, and ribosome recycling. The roles of essential proteins involved in each phase are described. All of the products of mitochondrial protein synthesis in mammals are inserted into the inner membrane. Several proteins that may help bind ribosomes to the membrane during translation are described, although much remains to be learned about this process. Mutations in mitochondrial or nuclear genes encoding components of the translation system often lead to severe deficiencies in oxidative phosphorylation, and a summary of these mutations is provided. This article is part of a Special Issue entitled: Mitochondrial Gene Expression."xsd:string
http://purl.uniprot.org/citations/22172991http://purl.org/dc/terms/identifier"doi:10.1016/j.bbagrm.2011.11.009"xsd:string
http://purl.uniprot.org/citations/22172991http://purl.uniprot.org/core/author"Spremulli L.L."xsd:string
http://purl.uniprot.org/citations/22172991http://purl.uniprot.org/core/author"Christian B.E."xsd:string
http://purl.uniprot.org/citations/22172991http://purl.uniprot.org/core/date"2012"xsd:gYear
http://purl.uniprot.org/citations/22172991http://purl.uniprot.org/core/name"Biochim Biophys Acta"xsd:string
http://purl.uniprot.org/citations/22172991http://purl.uniprot.org/core/pages"1035-1054"xsd:string
http://purl.uniprot.org/citations/22172991http://purl.uniprot.org/core/title"Mechanism of protein biosynthesis in mammalian mitochondria."xsd:string
http://purl.uniprot.org/citations/22172991http://purl.uniprot.org/core/volume"1819"xsd:string
http://purl.uniprot.org/citations/22172991http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/22172991
http://purl.uniprot.org/citations/22172991http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/22172991
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