| http://purl.uniprot.org/citations/22178260 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/22178260 | http://www.w3.org/2000/01/rdf-schema#comment | "Unusual drug accumulation is a common mechanism underlying serious drug-induced liver injury. Polymorphisms in three drug transporter genes (ABCB1, SLCO1B1 and ABCC2) may be risk markers for hepatitis induced by the unusual accumulation of anti-tuberculosis drugs (ATDs). We therefore investigated whether polymorphisms and haplotypes of these genes are associated with ATD-induced hepatitis by comparing the frequencies and distributions of single nucleotide polymorphisms and haplotypes of these three drug transporter genes among 67 patients with ATD-induced hepatitis and 159 patients tolerant to ATDs using a multivariate logistic regression analysis. We found that the frequencies of polymorphisms and haplotypes of ABCB1, SLCO1B1 and ABCC2 were similar in patients with ATD-induced hepatitis and ATD-tolerant controls. The present results suggest that these drug transporters do not play important roles in the pathogenesis of ATD-induced hepatitis in Korean patients."xsd:string |
| http://purl.uniprot.org/citations/22178260 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.tube.2011.09.007"xsd:string |
| http://purl.uniprot.org/citations/22178260 | http://purl.uniprot.org/core/author | "Lee J.H."xsd:string |
| http://purl.uniprot.org/citations/22178260 | http://purl.uniprot.org/core/author | "Kim Y.S."xsd:string |
| http://purl.uniprot.org/citations/22178260 | http://purl.uniprot.org/core/author | "Kim S.H."xsd:string |
| http://purl.uniprot.org/citations/22178260 | http://purl.uniprot.org/core/author | "Park J.S."xsd:string |
| http://purl.uniprot.org/citations/22178260 | http://purl.uniprot.org/core/author | "Lee B.H."xsd:string |
| http://purl.uniprot.org/citations/22178260 | http://purl.uniprot.org/core/author | "Kim S.H.'"xsd:string |
| http://purl.uniprot.org/citations/22178260 | http://purl.uniprot.org/core/author | "Jee Y.K."xsd:string |
| http://purl.uniprot.org/citations/22178260 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
| http://purl.uniprot.org/citations/22178260 | http://purl.uniprot.org/core/name | "Tuberculosis (Edinb)"xsd:string |
| http://purl.uniprot.org/citations/22178260 | http://purl.uniprot.org/core/pages | "100-104"xsd:string |
| http://purl.uniprot.org/citations/22178260 | http://purl.uniprot.org/core/title | "Polymorphisms in drug transporter genes (ABCB1, SLCO1B1 and ABCC2) and hepatitis induced by antituberculosis drugs."xsd:string |
| http://purl.uniprot.org/citations/22178260 | http://purl.uniprot.org/core/volume | "92"xsd:string |
| http://purl.uniprot.org/citations/22178260 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/22178260 |
| http://purl.uniprot.org/citations/22178260 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/22178260 |
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| http://purl.uniprot.org/uniprot/#_B5U2G4-mappedCitation-22178260 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22178260 |
| http://purl.uniprot.org/uniprot/#_F4ZUQ5-mappedCitation-22178260 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22178260 |
| http://purl.uniprot.org/uniprot/#_F4ZUT2-mappedCitation-22178260 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22178260 |