| http://purl.uniprot.org/citations/22212474 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/22212474 | http://www.w3.org/2000/01/rdf-schema#comment | "Ischemia and subsequent reperfusion (I/R) damage kidney tubular cells and consequently impair renal function. Rabbit bone marrow mesenchymal stem cells (BM-MSCs) expressing human bone morphogenic protein-7 (hBMP-7) regenerated tubular cells and improved renal function in a kidney I/R model. Rabbits were injected immediately after I/R with one of the following: (i) hBMP-7-transduced BM-MSCs (BM-MSCshBMP-7); (ii) enhanced green fluorescent protein-transduced BM-MSCs (BM-MSCsEGFP); or (iii) PBS. The activity of superoxide dismutase (SOD) was higher, and the amount of malondialdehyde (MDA) was lower in the BM-MSCshBMP-7 group than in the BM-MSCsEGFP group. Both the BM-MSCshBMP-7 group and the BM-MSCsEGFP group had higher SOD activity and lower amounts of MDA than the PBS group. Bcl-2- and Bcl-2-associated X protein levels, and other variables, indicated the regeneration of the kidney in both experimental groups. However, the BM-MSCs (hBMP-7) group showed higher activity than the BM-MSCsEGFP group, indicating that the combined strategy of BM-MSC transplantation with hBMP-7 gene therapy could be a useful approach for the treatment of renal IRI."xsd:string |
| http://purl.uniprot.org/citations/22212474 | http://purl.org/dc/terms/identifier | "doi:10.1111/j.1365-2443.2011.01572.x"xsd:string |
| http://purl.uniprot.org/citations/22212474 | http://purl.uniprot.org/core/author | "Wei C."xsd:string |
| http://purl.uniprot.org/citations/22212474 | http://purl.uniprot.org/core/author | "Ye G."xsd:string |
| http://purl.uniprot.org/citations/22212474 | http://purl.uniprot.org/core/author | "Bing-Wei Y."xsd:string |
| http://purl.uniprot.org/citations/22212474 | http://purl.uniprot.org/core/author | "Shan-Hong Y."xsd:string |
| http://purl.uniprot.org/citations/22212474 | http://purl.uniprot.org/core/author | "Wei-Sheng J."xsd:string |
| http://purl.uniprot.org/citations/22212474 | http://purl.uniprot.org/core/author | "Xiang-Wei W."xsd:string |
| http://purl.uniprot.org/citations/22212474 | http://purl.uniprot.org/core/author | "Yong-Liang L."xsd:string |
| http://purl.uniprot.org/citations/22212474 | http://purl.uniprot.org/core/author | "Yuan-Ning Z."xsd:string |
| http://purl.uniprot.org/citations/22212474 | http://purl.uniprot.org/core/author | "Zhen-Qiang F."xsd:string |
| http://purl.uniprot.org/citations/22212474 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
| http://purl.uniprot.org/citations/22212474 | http://purl.uniprot.org/core/name | "Genes Cells"xsd:string |
| http://purl.uniprot.org/citations/22212474 | http://purl.uniprot.org/core/pages | "53-64"xsd:string |
| http://purl.uniprot.org/citations/22212474 | http://purl.uniprot.org/core/title | "Localized expression of human BMP-7 by BM-MSCs enhances renal repair in an in vivo model of ischemia-reperfusion injury."xsd:string |
| http://purl.uniprot.org/citations/22212474 | http://purl.uniprot.org/core/volume | "17"xsd:string |
| http://purl.uniprot.org/citations/22212474 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/22212474 |
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