http://purl.uniprot.org/citations/22231121 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/22231121 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/22231121 | http://www.w3.org/2000/01/rdf-schema#comment | "RNA polymerase II (RNAP II) C-terminal domain (CTD) phosphorylation is important for various transcription-related processes. Here, we identify by affinity purification and mass spectrometry three previously uncharacterized human CTD-interaction domain (CID)-containing proteins, RPRD1A, RPRD1B and RPRD2, which co-purify with RNAP II and three other RNAP II-associated proteins, RPAP2, GRINL1A and RECQL5, but not with the Mediator complex. RPRD1A and RPRD1B can accompany RNAP II from promoter regions to 3'-untranslated regions during transcription in vivo, predominantly interact with phosphorylated RNAP II, and can reduce CTD S5- and S7-phosphorylated RNAP II at target gene promoters. Thus, the RPRD proteins are likely to have multiple important roles in transcription."xsd:string |
http://purl.uniprot.org/citations/22231121 | http://purl.org/dc/terms/identifier | "doi:10.4161/trns.2.5.17803"xsd:string |
http://purl.uniprot.org/citations/22231121 | http://purl.org/dc/terms/identifier | "doi:10.4161/trns.2.5.17803"xsd:string |
http://purl.uniprot.org/citations/22231121 | http://purl.uniprot.org/core/author | "Guo X."xsd:string |
http://purl.uniprot.org/citations/22231121 | http://purl.uniprot.org/core/author | "Guo X."xsd:string |
http://purl.uniprot.org/citations/22231121 | http://purl.uniprot.org/core/author | "Li J."xsd:string |
http://purl.uniprot.org/citations/22231121 | http://purl.uniprot.org/core/author | "Li J."xsd:string |
http://purl.uniprot.org/citations/22231121 | http://purl.uniprot.org/core/author | "Guo H."xsd:string |
http://purl.uniprot.org/citations/22231121 | http://purl.uniprot.org/core/author | "Guo H."xsd:string |
http://purl.uniprot.org/citations/22231121 | http://purl.uniprot.org/core/author | "Marcon E."xsd:string |
http://purl.uniprot.org/citations/22231121 | http://purl.uniprot.org/core/author | "Marcon E."xsd:string |
http://purl.uniprot.org/citations/22231121 | http://purl.uniprot.org/core/author | "Young P."xsd:string |
http://purl.uniprot.org/citations/22231121 | http://purl.uniprot.org/core/author | "Young P."xsd:string |
http://purl.uniprot.org/citations/22231121 | http://purl.uniprot.org/core/author | "Emili A."xsd:string |
http://purl.uniprot.org/citations/22231121 | http://purl.uniprot.org/core/author | "Emili A."xsd:string |
http://purl.uniprot.org/citations/22231121 | http://purl.uniprot.org/core/author | "Greenblatt J.F."xsd:string |
http://purl.uniprot.org/citations/22231121 | http://purl.uniprot.org/core/author | "Greenblatt J.F."xsd:string |
http://purl.uniprot.org/citations/22231121 | http://purl.uniprot.org/core/author | "Zhong G."xsd:string |
http://purl.uniprot.org/citations/22231121 | http://purl.uniprot.org/core/author | "Zhong G."xsd:string |
http://purl.uniprot.org/citations/22231121 | http://purl.uniprot.org/core/author | "Moffat J."xsd:string |
http://purl.uniprot.org/citations/22231121 | http://purl.uniprot.org/core/author | "Moffat J."xsd:string |
http://purl.uniprot.org/citations/22231121 | http://purl.uniprot.org/core/author | "Ni Z."xsd:string |
http://purl.uniprot.org/citations/22231121 | http://purl.uniprot.org/core/author | "Ni Z."xsd:string |