RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/22248276http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/22248276http://www.w3.org/2000/01/rdf-schema#comment"Iron overload increases the risk of infections, veno-occlusive disease and hepatic dysfunction in post-transplant period. Our objective was to investigate the association of pre-transplant ferritin levels with complications and survival after allogeneic hematopoietic stem cell transplantation (alloHSCT).We retrospectively analysed 84 patients' data who had undergone allogeneic HSCT into two groups: patients with a serum ferritin level ≥ 1000 ng/ml, and patients with <1000 ng/ml at the time of HSCT.Cox-regression analysis showed that pre-transplant serum ferritin levels were significantly higher in patients who had at least one infectious event compared with those who had no any infectious event in the post-transplant 100 days (p<0.023). Overall survival (OS) and disease-free survival (DFS) rates were significantly higher in patients with a time-to-tx interval 12 months (p=0.002 and p=0.008 respectively). A higher risk of death was observed in high-ferritin group (hazard ratio=2.27, CI:1.01-5.09, p=0.023 for OS and hazard ratio=2.49, CI:1.12-5.53 p=0.039 for DFS). No significant effect on OS and DFS among groups was observed for variables conditioning regimen, gender and diagnosis. Acute GVHD was more common in patients with a ferritin level ≥ 1000 ng /mL, but this was not statistically significant (p>0.05). There was no statistical significance in both groups (ferritin ≥ 1000 ng /mL and ferritin <1000 ng/mL) for relapse rates (p>0.05). Platelet and neutrophil engaftment day was not found statistically significant compared with both groups (p=0.273 and p=0.882, respectively). Pre-transplant ferritin levels may predict poor outcomes in patients who had undergone allogeneic hematopoietic stem cell transplantation."xsd:string
http://purl.uniprot.org/citations/22248276http://purl.org/dc/terms/identifier"doi:10.4149/neo_2012_024"xsd:string
http://purl.uniprot.org/citations/22248276http://purl.uniprot.org/core/author"Cetin M."xsd:string
http://purl.uniprot.org/citations/22248276http://purl.uniprot.org/core/author"Unal A."xsd:string
http://purl.uniprot.org/citations/22248276http://purl.uniprot.org/core/author"Ozturk A."xsd:string
http://purl.uniprot.org/citations/22248276http://purl.uniprot.org/core/author"Eser B."xsd:string
http://purl.uniprot.org/citations/22248276http://purl.uniprot.org/core/author"Kaynar L."xsd:string
http://purl.uniprot.org/citations/22248276http://purl.uniprot.org/core/author"Baldane S."xsd:string
http://purl.uniprot.org/citations/22248276http://purl.uniprot.org/core/author"Kurnaz F."xsd:string
http://purl.uniprot.org/citations/22248276http://purl.uniprot.org/core/author"Pala C."xsd:string
http://purl.uniprot.org/citations/22248276http://purl.uniprot.org/core/author"Sivgin S."xsd:string
http://purl.uniprot.org/citations/22248276http://purl.uniprot.org/core/date"2012"xsd:gYear
http://purl.uniprot.org/citations/22248276http://purl.uniprot.org/core/name"Neoplasma"xsd:string
http://purl.uniprot.org/citations/22248276http://purl.uniprot.org/core/pages"183-190"xsd:string
http://purl.uniprot.org/citations/22248276http://purl.uniprot.org/core/title"Pretransplant serum ferritin level may be a predictive marker for outcomes in patients having undergone allogeneic hematopoietic stem cell transplantation."xsd:string
http://purl.uniprot.org/citations/22248276http://purl.uniprot.org/core/volume"59"xsd:string
http://purl.uniprot.org/citations/22248276http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/22248276
http://purl.uniprot.org/citations/22248276http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/22248276
http://purl.uniprot.org/uniprot/#_A0A384MDR3-mappedCitation-22248276http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/22248276
http://purl.uniprot.org/uniprot/#_B1Q387-mappedCitation-22248276http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/22248276
http://purl.uniprot.org/uniprot/#_B1Q3B3-mappedCitation-22248276http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/22248276
http://purl.uniprot.org/uniprot/#_B1Q3B4-mappedCitation-22248276http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/22248276
http://purl.uniprot.org/uniprot/#_M1KCE4-mappedCitation-22248276http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/22248276
http://purl.uniprot.org/uniprot/#_O00563-mappedCitation-22248276http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/22248276