| http://purl.uniprot.org/citations/22266736 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/22266736 | http://www.w3.org/2000/01/rdf-schema#comment | "Three new steroids 3-oxocholest-1,22-dien-12β-ol (1), 3-oxocholest-1,4-dien-20β-ol (2), 3-oxocholest-1,4-dien-12β-ol (3), and three known steroids (20S)-20-Hydroxyergosta-1,4,24(28)-trien-3-one (4) [7a], 5α,8α-Epidioxycholesta-6,22-dien-3β-ol (5) [10] and 5-cholestene-3β,12β-diol (6) [11] were isolated from a soft coral Dendronephthya gigantea. Their chemical structures and relative stereochemistry were elucidated by the analysis of HRMS and 2-D NMR spectroscopic data. The steroids 1 and 2 showed notable inhibitory activity against farnesoid X-activated receptor (FXR) with IC(50)'s 14 and 15μM."xsd:string |
| http://purl.uniprot.org/citations/22266736 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.steroids.2011.12.027"xsd:string |
| http://purl.uniprot.org/citations/22266736 | http://purl.uniprot.org/core/author | "Kang H."xsd:string |
| http://purl.uniprot.org/citations/22266736 | http://purl.uniprot.org/core/author | "Kim H."xsd:string |
| http://purl.uniprot.org/citations/22266736 | http://purl.uniprot.org/core/author | "Lee J."xsd:string |
| http://purl.uniprot.org/citations/22266736 | http://purl.uniprot.org/core/author | "Choi H."xsd:string |
| http://purl.uniprot.org/citations/22266736 | http://purl.uniprot.org/core/author | "Hwang H."xsd:string |
| http://purl.uniprot.org/citations/22266736 | http://purl.uniprot.org/core/author | "Kang E."xsd:string |
| http://purl.uniprot.org/citations/22266736 | http://purl.uniprot.org/core/author | "Hahn D."xsd:string |
| http://purl.uniprot.org/citations/22266736 | http://purl.uniprot.org/core/author | "Ham J."xsd:string |
| http://purl.uniprot.org/citations/22266736 | http://purl.uniprot.org/core/author | "Chin J."xsd:string |
| http://purl.uniprot.org/citations/22266736 | http://purl.uniprot.org/core/author | "Nam S.J."xsd:string |
| http://purl.uniprot.org/citations/22266736 | http://purl.uniprot.org/core/author | "Shin K."xsd:string |
| http://purl.uniprot.org/citations/22266736 | http://purl.uniprot.org/core/author | "Won D.H."xsd:string |
| http://purl.uniprot.org/citations/22266736 | http://purl.uniprot.org/core/author | "Ju M.K."xsd:string |
| http://purl.uniprot.org/citations/22266736 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
| http://purl.uniprot.org/citations/22266736 | http://purl.uniprot.org/core/name | "Steroids"xsd:string |
| http://purl.uniprot.org/citations/22266736 | http://purl.uniprot.org/core/pages | "355-359"xsd:string |
| http://purl.uniprot.org/citations/22266736 | http://purl.uniprot.org/core/title | "Sterols from a soft coral, Dendronephthya gigantea as farnesoid X-activated receptor antagonists."xsd:string |
| http://purl.uniprot.org/citations/22266736 | http://purl.uniprot.org/core/volume | "77"xsd:string |
| http://purl.uniprot.org/citations/22266736 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/22266736 |
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| http://purl.uniprot.org/uniprot/#_B7Z423-mappedCitation-22266736 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22266736 |