| http://purl.uniprot.org/citations/22285184 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/22285184 | http://www.w3.org/2000/01/rdf-schema#comment | "The murine SWI/SNF-like BAF complex is an ATP-dependent chromatin remodeling complex that functions as a transcriptional regulator in cell proliferation, differentiation and development. The SWI/SNF-like BAF complex consists of several components including core subunits such as BRG1, BAF155/SRG3, BAF47/SNF5/INI1, and BAF170. We have previously shown that the interaction between SRG3/mBAF155 and other components of the complex stabilizes them by attenuating their proteasomal degradation. However, it has not been known how the major components of the SWI/SNF-like BAF complex such as BRG1, SNF5, and BAF60a are targeted for the ubiquitination and degradation, and how SRG3/mBAF155 protects them from the degradation process. Here we report that CHFR interacts with BRG1, SNF5, and BAF60a of the SWI/SNF-like BAF complex and ubiquitinates them to target for degradation through a proteasome-mediated pathway, and that SRG3/mBAF155 stabilizes these components by blocking their interaction with CHFR."xsd:string |
| http://purl.uniprot.org/citations/22285184 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbrc.2012.01.057"xsd:string |
| http://purl.uniprot.org/citations/22285184 | http://purl.uniprot.org/core/author | "Kim J.M."xsd:string |
| http://purl.uniprot.org/citations/22285184 | http://purl.uniprot.org/core/author | "Choi J."xsd:string |
| http://purl.uniprot.org/citations/22285184 | http://purl.uniprot.org/core/author | "Seol J.H."xsd:string |
| http://purl.uniprot.org/citations/22285184 | http://purl.uniprot.org/core/author | "Jeon S."xsd:string |
| http://purl.uniprot.org/citations/22285184 | http://purl.uniprot.org/core/author | "Sohn D.H."xsd:string |
| http://purl.uniprot.org/citations/22285184 | http://purl.uniprot.org/core/author | "Seong R.H."xsd:string |
| http://purl.uniprot.org/citations/22285184 | http://purl.uniprot.org/core/author | "Jung I."xsd:string |
| http://purl.uniprot.org/citations/22285184 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
| http://purl.uniprot.org/citations/22285184 | http://purl.uniprot.org/core/name | "Biochem Biophys Res Commun"xsd:string |
| http://purl.uniprot.org/citations/22285184 | http://purl.uniprot.org/core/pages | "512-517"xsd:string |
| http://purl.uniprot.org/citations/22285184 | http://purl.uniprot.org/core/title | "SRG3/mBAF155 stabilizes the SWI/SNF-like BAF complex by blocking CHFR mediated ubiquitination and degradation of its major components."xsd:string |
| http://purl.uniprot.org/citations/22285184 | http://purl.uniprot.org/core/volume | "418"xsd:string |
| http://purl.uniprot.org/citations/22285184 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/22285184 |
| http://purl.uniprot.org/citations/22285184 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/22285184 |
| http://purl.uniprot.org/uniprot/Q810L3#attribution-54163E40420C70FE328167D1337F2BA2 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/22285184 |
| http://purl.uniprot.org/uniprot/P97496#attribution-54163E40420C70FE328167D1337F2BA2 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/22285184 |
| http://purl.uniprot.org/uniprot/#_A0A0G2JDG0-mappedCitation-22285184 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22285184 |
| http://purl.uniprot.org/uniprot/#_A0A0G2JG18-mappedCitation-22285184 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22285184 |
| http://purl.uniprot.org/uniprot/#_A0A0G2JGX6-mappedCitation-22285184 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22285184 |
| http://purl.uniprot.org/uniprot/#_A0A0R4J170-mappedCitation-22285184 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22285184 |
| http://purl.uniprot.org/uniprot/#_A0A0G2JFC1-mappedCitation-22285184 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22285184 |
| http://purl.uniprot.org/uniprot/#_A0A0G2JFJ8-mappedCitation-22285184 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22285184 |