http://purl.uniprot.org/citations/22285492 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/22285492 | http://www.w3.org/2000/01/rdf-schema#comment | "Characteristic differences of prions may account for the conformational diversity of the pathogenic isoform of prion protein (PrP(Sc)). Here, we applied a protein detection procedure by using fluorescent-labelled peptides for detecting PrP(Sc). Five prion protein (PrP) related peptides were found to change significantly their fluorescent intensities with prion-affected animal samples. Their reactivity was different among atypical L-BSE, classical BSE and scrapie. The pull-down assay revealed that they precipitated PrP(Sc) specifically. These findings suggest that fluorescent intensity changes depend on peptide-PrP(Sc) binding. This novel approach may distinguish the fine structural differences in PrP(Sc), which were not detected by the pull-down assay."xsd:string |
http://purl.uniprot.org/citations/22285492 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2012.01.012"xsd:string |
http://purl.uniprot.org/citations/22285492 | http://purl.uniprot.org/core/author | "Ohyama T."xsd:string |
http://purl.uniprot.org/citations/22285492 | http://purl.uniprot.org/core/author | "Hirata A."xsd:string |
http://purl.uniprot.org/citations/22285492 | http://purl.uniprot.org/core/author | "Kasai K."xsd:string |
http://purl.uniprot.org/citations/22285492 | http://purl.uniprot.org/core/author | "Yokoyama T."xsd:string |
http://purl.uniprot.org/citations/22285492 | http://purl.uniprot.org/core/author | "Nokihara K."xsd:string |
http://purl.uniprot.org/citations/22285492 | http://purl.uniprot.org/core/author | "Mohri S."xsd:string |
http://purl.uniprot.org/citations/22285492 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
http://purl.uniprot.org/citations/22285492 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
http://purl.uniprot.org/citations/22285492 | http://purl.uniprot.org/core/pages | "325-329"xsd:string |
http://purl.uniprot.org/citations/22285492 | http://purl.uniprot.org/core/title | "Novel assay with fluorescence-labelled PrP peptides for differentiating L-type atypical and classical BSEs, and scrapie."xsd:string |
http://purl.uniprot.org/citations/22285492 | http://purl.uniprot.org/core/volume | "586"xsd:string |
http://purl.uniprot.org/citations/22285492 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/22285492 |
http://purl.uniprot.org/citations/22285492 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/22285492 |
http://purl.uniprot.org/uniprot/#_P10279-mappedCitation-22285492 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22285492 |
http://purl.uniprot.org/uniprot/#_P23907-mappedCitation-22285492 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22285492 |
http://purl.uniprot.org/uniprot/#_Q3TZI7-mappedCitation-22285492 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22285492 |
http://purl.uniprot.org/uniprot/#_Q3UG89-mappedCitation-22285492 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22285492 |
http://purl.uniprot.org/uniprot/#_P04156-mappedCitation-22285492 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22285492 |
http://purl.uniprot.org/uniprot/#_P04925-mappedCitation-22285492 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22285492 |
http://purl.uniprot.org/uniprot/#_Q3UBH0-mappedCitation-22285492 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22285492 |
http://purl.uniprot.org/uniprot/#_Q4FJQ7-mappedCitation-22285492 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22285492 |
http://purl.uniprot.org/uniprot/#_Q3UF68-mappedCitation-22285492 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22285492 |