| http://purl.uniprot.org/citations/22286215 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/22286215 | http://www.w3.org/2000/01/rdf-schema#comment | "The nematode Caenorhabditis elegans is central to research in molecular, cell and developmental biology, but nearly all of this research has been conducted on a single strain of C. elegans. Little is known about the population genomic and evolutionary history of this species. We characterized C. elegans genetic variation using high-throughput selective sequencing of a worldwide collection of 200 wild strains and identified 41,188 SNPs. Notably, C. elegans genome variation is dominated by a set of commonly shared haplotypes on four of its six chromosomes, each spanning many megabases. Population genetic modeling showed that this pattern was generated by chromosome-scale selective sweeps that have reduced variation worldwide; at least one of these sweeps probably occurred in the last few hundred years. These sweeps, which we hypothesize to be a result of human activity, have drastically reshaped the global C. elegans population in the recent past."xsd:string |
| http://purl.uniprot.org/citations/22286215 | http://purl.org/dc/terms/identifier | "doi:10.1038/ng.1050"xsd:string |
| http://purl.uniprot.org/citations/22286215 | http://purl.uniprot.org/core/author | "Ghosh R."xsd:string |
| http://purl.uniprot.org/citations/22286215 | http://purl.uniprot.org/core/author | "Kruglyak L."xsd:string |
| http://purl.uniprot.org/citations/22286215 | http://purl.uniprot.org/core/author | "Shapiro J.A."xsd:string |
| http://purl.uniprot.org/citations/22286215 | http://purl.uniprot.org/core/author | "Bloom J.S."xsd:string |
| http://purl.uniprot.org/citations/22286215 | http://purl.uniprot.org/core/author | "Andersen E.C."xsd:string |
| http://purl.uniprot.org/citations/22286215 | http://purl.uniprot.org/core/author | "Felix M.A."xsd:string |
| http://purl.uniprot.org/citations/22286215 | http://purl.uniprot.org/core/author | "Gerke J.P."xsd:string |
| http://purl.uniprot.org/citations/22286215 | http://purl.uniprot.org/core/author | "Crissman J.R."xsd:string |
| http://purl.uniprot.org/citations/22286215 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
| http://purl.uniprot.org/citations/22286215 | http://purl.uniprot.org/core/name | "Nat Genet"xsd:string |
| http://purl.uniprot.org/citations/22286215 | http://purl.uniprot.org/core/pages | "285-290"xsd:string |
| http://purl.uniprot.org/citations/22286215 | http://purl.uniprot.org/core/title | "Chromosome-scale selective sweeps shape Caenorhabditis elegans genomic diversity."xsd:string |
| http://purl.uniprot.org/citations/22286215 | http://purl.uniprot.org/core/volume | "44"xsd:string |
| http://purl.uniprot.org/citations/22286215 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/22286215 |
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