| http://purl.uniprot.org/citations/22304919 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/22304919 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/22304919 | http://www.w3.org/2000/01/rdf-schema#comment | "Budding of COPI-coated vesicles from Golgi membranes requires an Arf family G protein and the coatomer complex recruited from cytosol. Arf is also required with coatomer-related clathrin adaptor complexes to bud vesicles from the trans-Golgi network and endosomal compartments. To understand the structural basis for Arf-dependent recruitment of a vesicular coat to the membrane, we determined the structure of Arf1 bound to the γζ-COP subcomplex of coatomer. Structure-guided biochemical analysis reveals that a second Arf1-GTP molecule binds to βδ-COP at a site common to the γ- and β-COP subunits. The Arf1-binding sites on coatomer are spatially related to PtdIns4,5P(2)-binding sites on the endocytic AP2 complex, providing evidence that the orientation of membrane binding is general for this class of vesicular coat proteins. A bivalent GTP-dependent binding mode has implications for the dynamics of coatomer interaction with the Golgi and for the selection of cargo molecules."xsd:string |
| http://purl.uniprot.org/citations/22304919 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.cell.2012.01.015"xsd:string |
| http://purl.uniprot.org/citations/22304919 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.cell.2012.01.015"xsd:string |
| http://purl.uniprot.org/citations/22304919 | http://purl.uniprot.org/core/author | "Goldberg J."xsd:string |
| http://purl.uniprot.org/citations/22304919 | http://purl.uniprot.org/core/author | "Goldberg J."xsd:string |
| http://purl.uniprot.org/citations/22304919 | http://purl.uniprot.org/core/author | "Yu X."xsd:string |
| http://purl.uniprot.org/citations/22304919 | http://purl.uniprot.org/core/author | "Yu X."xsd:string |
| http://purl.uniprot.org/citations/22304919 | http://purl.uniprot.org/core/author | "Breitman M."xsd:string |
| http://purl.uniprot.org/citations/22304919 | http://purl.uniprot.org/core/author | "Breitman M."xsd:string |
| http://purl.uniprot.org/citations/22304919 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
| http://purl.uniprot.org/citations/22304919 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
| http://purl.uniprot.org/citations/22304919 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
| http://purl.uniprot.org/citations/22304919 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
| http://purl.uniprot.org/citations/22304919 | http://purl.uniprot.org/core/pages | "530-542"xsd:string |
| http://purl.uniprot.org/citations/22304919 | http://purl.uniprot.org/core/pages | "530-542"xsd:string |
| http://purl.uniprot.org/citations/22304919 | http://purl.uniprot.org/core/title | "A structure-based mechanism for Arf1-dependent recruitment of coatomer to membranes."xsd:string |
| http://purl.uniprot.org/citations/22304919 | http://purl.uniprot.org/core/title | "A structure-based mechanism for Arf1-dependent recruitment of coatomer to membranes."xsd:string |
| http://purl.uniprot.org/citations/22304919 | http://purl.uniprot.org/core/volume | "148"xsd:string |
| http://purl.uniprot.org/citations/22304919 | http://purl.uniprot.org/core/volume | "148"xsd:string |
| http://purl.uniprot.org/citations/22304919 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/22304919 |
| http://purl.uniprot.org/citations/22304919 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/22304919 |
| http://purl.uniprot.org/citations/22304919 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/22304919 |
| http://purl.uniprot.org/citations/22304919 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/22304919 |