| http://purl.uniprot.org/citations/22306737 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/22306737 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/22306737 | http://www.w3.org/2000/01/rdf-schema#comment | "Visual arrestin specifically binds to photoactivated and phosphorylated rhodopsin and inactivates phototransduction. In contrast, the p44 splice variant can terminate phototransduction by binding to nonphosphorylated light-activated rhodopsin. Here we report the crystal structure of bovine p44 at a resolution of 1.85 Å. Compared to native arrestin, the p44 structure reveals significant differences in regions crucial for receptor binding, namely flexible loop V-VI and polar core regions. Additionally, electrostatic potential is remarkably positive on the N-domain and the C-domain. The p44 structure represents an active conformation that serves as a model to explain the 'constitutive activity' found in arrestin variants."xsd:string |
| http://purl.uniprot.org/citations/22306737 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.jmb.2012.01.028"xsd:string |
| http://purl.uniprot.org/citations/22306737 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.jmb.2012.01.028"xsd:string |
| http://purl.uniprot.org/citations/22306737 | http://purl.uniprot.org/core/author | "Weirauch M."xsd:string |
| http://purl.uniprot.org/citations/22306737 | http://purl.uniprot.org/core/author | "Weirauch M."xsd:string |
| http://purl.uniprot.org/citations/22306737 | http://purl.uniprot.org/core/author | "Granzin J."xsd:string |
| http://purl.uniprot.org/citations/22306737 | http://purl.uniprot.org/core/author | "Granzin J."xsd:string |
| http://purl.uniprot.org/citations/22306737 | http://purl.uniprot.org/core/author | "Schlesinger R."xsd:string |
| http://purl.uniprot.org/citations/22306737 | http://purl.uniprot.org/core/author | "Schlesinger R."xsd:string |
| http://purl.uniprot.org/citations/22306737 | http://purl.uniprot.org/core/author | "Batra-Safferling R."xsd:string |
| http://purl.uniprot.org/citations/22306737 | http://purl.uniprot.org/core/author | "Batra-Safferling R."xsd:string |
| http://purl.uniprot.org/citations/22306737 | http://purl.uniprot.org/core/author | "Buldt G."xsd:string |
| http://purl.uniprot.org/citations/22306737 | http://purl.uniprot.org/core/author | "Buldt G."xsd:string |
| http://purl.uniprot.org/citations/22306737 | http://purl.uniprot.org/core/author | "Cousin A."xsd:string |
| http://purl.uniprot.org/citations/22306737 | http://purl.uniprot.org/core/author | "Cousin A."xsd:string |
| http://purl.uniprot.org/citations/22306737 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
| http://purl.uniprot.org/citations/22306737 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
| http://purl.uniprot.org/citations/22306737 | http://purl.uniprot.org/core/name | "J. Mol. Biol."xsd:string |
| http://purl.uniprot.org/citations/22306737 | http://purl.uniprot.org/core/name | "J. Mol. Biol."xsd:string |
| http://purl.uniprot.org/citations/22306737 | http://purl.uniprot.org/core/pages | "611-618"xsd:string |
| http://purl.uniprot.org/citations/22306737 | http://purl.uniprot.org/core/pages | "611-618"xsd:string |
| http://purl.uniprot.org/citations/22306737 | http://purl.uniprot.org/core/title | "Crystal structure of p44, a constitutively active splice variant of visual arrestin."xsd:string |
| http://purl.uniprot.org/citations/22306737 | http://purl.uniprot.org/core/title | "Crystal structure of p44, a constitutively active splice variant of visual arrestin."xsd:string |