http://purl.uniprot.org/citations/22326224 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/22326224 | http://www.w3.org/2000/01/rdf-schema#comment | "Progress has been made in elucidating the cell-surface phenotype of primary adipose progenitors; however, specific functional markers and distinct molecular signatures of fat depot-specific preadipocytes have remained elusive. In this study, we label committed murine adipose progenitors through expression of GFP from the genetic locus for Zfp423, a gene controlling preadipocyte determination. Selection of GFP-expressing fibroblasts from either subcutaneous or visceral adipose-derived stromal vascular cultures isolates stably committed preadipocytes that undergo robust adipogenesis. Immunohistochemistry for Zfp423-driven GFP expression in vivo confirms a perivascular origin of preadipocytes within both white and brown adipose tissues. Interestingly, a small subset of capillary endothelial cells within white and brown fat also express this marker, suggesting a contribution of specialized endothelial cells to the adipose lineage. Zfp423(GFP) mice represent a simple tool for the specific localization and isolation of molecularly defined preadipocytes from distinct adipose tissue depots."xsd:string |
http://purl.uniprot.org/citations/22326224 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.cmet.2012.01.010"xsd:string |
http://purl.uniprot.org/citations/22326224 | http://purl.uniprot.org/core/author | "Ye L."xsd:string |
http://purl.uniprot.org/citations/22326224 | http://purl.uniprot.org/core/author | "Spiegelman B.M."xsd:string |
http://purl.uniprot.org/citations/22326224 | http://purl.uniprot.org/core/author | "Cohen P."xsd:string |
http://purl.uniprot.org/citations/22326224 | http://purl.uniprot.org/core/author | "Gupta R.K."xsd:string |
http://purl.uniprot.org/citations/22326224 | http://purl.uniprot.org/core/author | "Lo J.C."xsd:string |
http://purl.uniprot.org/citations/22326224 | http://purl.uniprot.org/core/author | "Cinti S."xsd:string |
http://purl.uniprot.org/citations/22326224 | http://purl.uniprot.org/core/author | "Frontini A."xsd:string |
http://purl.uniprot.org/citations/22326224 | http://purl.uniprot.org/core/author | "Kleiner S."xsd:string |
http://purl.uniprot.org/citations/22326224 | http://purl.uniprot.org/core/author | "Khandekar M.J."xsd:string |
http://purl.uniprot.org/citations/22326224 | http://purl.uniprot.org/core/author | "Mepani R.J."xsd:string |
http://purl.uniprot.org/citations/22326224 | http://purl.uniprot.org/core/author | "Bhowmick D.C."xsd:string |
http://purl.uniprot.org/citations/22326224 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
http://purl.uniprot.org/citations/22326224 | http://purl.uniprot.org/core/name | "Cell Metab"xsd:string |
http://purl.uniprot.org/citations/22326224 | http://purl.uniprot.org/core/pages | "230-239"xsd:string |
http://purl.uniprot.org/citations/22326224 | http://purl.uniprot.org/core/title | "Zfp423 expression identifies committed preadipocytes and localizes to adipose endothelial and perivascular cells."xsd:string |
http://purl.uniprot.org/citations/22326224 | http://purl.uniprot.org/core/volume | "15"xsd:string |
http://purl.uniprot.org/citations/22326224 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/22326224 |
http://purl.uniprot.org/citations/22326224 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/22326224 |
http://purl.uniprot.org/uniprot/#_G3UYI9-mappedCitation-22326224 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22326224 |
http://purl.uniprot.org/uniprot/#_G3UZP1-mappedCitation-22326224 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22326224 |
http://purl.uniprot.org/uniprot/#_G3UW89-mappedCitation-22326224 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22326224 |
http://purl.uniprot.org/uniprot/#_Q3V017-mappedCitation-22326224 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22326224 |