| http://purl.uniprot.org/citations/22327622 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/22327622 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/22327622 | http://www.w3.org/2000/01/rdf-schema#comment | "Applying a next-generation sequencing assay targeting 145 cancer-relevant genes in 40 colorectal cancer and 24 non-small cell lung cancer formalin-fixed paraffin-embedded tissue specimens identified at least one clinically relevant genomic alteration in 59% of the samples and revealed two gene fusions, C2orf44-ALK in a colorectal cancer sample and KIF5B-RET in a lung adenocarcinoma. Further screening of 561 lung adenocarcinomas identified 11 additional tumors with KIF5B-RET gene fusions (2.0%; 95% CI 0.8-3.1%). Cells expressing oncogenic KIF5B-RET are sensitive to multi-kinase inhibitors that inhibit RET."xsd:string |
| http://purl.uniprot.org/citations/22327622 | http://purl.org/dc/terms/identifier | "doi:10.1038/nm.2673"xsd:string |
| http://purl.uniprot.org/citations/22327622 | http://purl.org/dc/terms/identifier | "doi:10.1038/nm.2673"xsd:string |
| http://purl.uniprot.org/citations/22327622 | http://purl.uniprot.org/core/author | "Bloom T."xsd:string |
| http://purl.uniprot.org/citations/22327622 | http://purl.uniprot.org/core/author | "Bloom T."xsd:string |
| http://purl.uniprot.org/citations/22327622 | http://purl.uniprot.org/core/author | "Kim J."xsd:string |
| http://purl.uniprot.org/citations/22327622 | http://purl.uniprot.org/core/author | "Kim J."xsd:string |
| http://purl.uniprot.org/citations/22327622 | http://purl.uniprot.org/core/author | "Parker A."xsd:string |
| http://purl.uniprot.org/citations/22327622 | http://purl.uniprot.org/core/author | "Parker A."xsd:string |
| http://purl.uniprot.org/citations/22327622 | http://purl.uniprot.org/core/author | "Kim H.R."xsd:string |
| http://purl.uniprot.org/citations/22327622 | http://purl.uniprot.org/core/author | "Kim H.R."xsd:string |
| http://purl.uniprot.org/citations/22327622 | http://purl.uniprot.org/core/author | "White J."xsd:string |
| http://purl.uniprot.org/citations/22327622 | http://purl.uniprot.org/core/author | "White J."xsd:string |
| http://purl.uniprot.org/citations/22327622 | http://purl.uniprot.org/core/author | "Balasubramanian S."xsd:string |
| http://purl.uniprot.org/citations/22327622 | http://purl.uniprot.org/core/author | "Balasubramanian S."xsd:string |
| http://purl.uniprot.org/citations/22327622 | http://purl.uniprot.org/core/author | "Sasaki H."xsd:string |
| http://purl.uniprot.org/citations/22327622 | http://purl.uniprot.org/core/author | "Sasaki H."xsd:string |
| http://purl.uniprot.org/citations/22327622 | http://purl.uniprot.org/core/author | "White E."xsd:string |
| http://purl.uniprot.org/citations/22327622 | http://purl.uniprot.org/core/author | "White E."xsd:string |
| http://purl.uniprot.org/citations/22327622 | http://purl.uniprot.org/core/author | "Park S.I."xsd:string |
| http://purl.uniprot.org/citations/22327622 | http://purl.uniprot.org/core/author | "Park S.I."xsd:string |
| http://purl.uniprot.org/citations/22327622 | http://purl.uniprot.org/core/author | "Curran J.A."xsd:string |
| http://purl.uniprot.org/citations/22327622 | http://purl.uniprot.org/core/author | "Curran J.A."xsd:string |