http://purl.uniprot.org/citations/22340591 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/22340591 | http://www.w3.org/2000/01/rdf-schema#comment | "Medulloblastomas that display a large cell/anaplastic morphology and overexpress the cellular c-MYC gene are highly aggressive and carry a very poor prognosis. This so-called MYC-subgroup differs in its histopathology, gene expression profile, and clinical behavior from other forms of medulloblastoma. We generated a mouse model of MYC-subgroup medulloblastoma by transducing Trp53-null cerebellar progenitor cells with Myc. The cardinal features of these mouse medulloblastomas closely mimic those of human MYC-subgroup tumors and significantly differ from mouse models of the Sonic-Hedgehog- and WNT-disease subgroups. This mouse model should significantly accelerate understanding and treatment of the most aggressive form of medulloblastoma and infers distinct roles for MYC and MYCN in tumorigenesis."xsd:string |
http://purl.uniprot.org/citations/22340591 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.ccr.2011.12.023"xsd:string |
http://purl.uniprot.org/citations/22340591 | http://purl.uniprot.org/core/author | "Gao C."xsd:string |
http://purl.uniprot.org/citations/22340591 | http://purl.uniprot.org/core/author | "Ellison D.W."xsd:string |
http://purl.uniprot.org/citations/22340591 | http://purl.uniprot.org/core/author | "Qu C."xsd:string |
http://purl.uniprot.org/citations/22340591 | http://purl.uniprot.org/core/author | "Finkelstein D."xsd:string |
http://purl.uniprot.org/citations/22340591 | http://purl.uniprot.org/core/author | "Gilbertson R.J."xsd:string |
http://purl.uniprot.org/citations/22340591 | http://purl.uniprot.org/core/author | "Roussel M.F."xsd:string |
http://purl.uniprot.org/citations/22340591 | http://purl.uniprot.org/core/author | "Uziel T."xsd:string |
http://purl.uniprot.org/citations/22340591 | http://purl.uniprot.org/core/author | "Pounds S."xsd:string |
http://purl.uniprot.org/citations/22340591 | http://purl.uniprot.org/core/author | "Robinson G."xsd:string |
http://purl.uniprot.org/citations/22340591 | http://purl.uniprot.org/core/author | "Gibson P."xsd:string |
http://purl.uniprot.org/citations/22340591 | http://purl.uniprot.org/core/author | "Rehg J."xsd:string |
http://purl.uniprot.org/citations/22340591 | http://purl.uniprot.org/core/author | "Kawauchi D."xsd:string |
http://purl.uniprot.org/citations/22340591 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
http://purl.uniprot.org/citations/22340591 | http://purl.uniprot.org/core/name | "Cancer Cell"xsd:string |
http://purl.uniprot.org/citations/22340591 | http://purl.uniprot.org/core/pages | "168-180"xsd:string |
http://purl.uniprot.org/citations/22340591 | http://purl.uniprot.org/core/title | "A mouse model of the most aggressive subgroup of human medulloblastoma."xsd:string |
http://purl.uniprot.org/citations/22340591 | http://purl.uniprot.org/core/volume | "21"xsd:string |
http://purl.uniprot.org/citations/22340591 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/22340591 |
http://purl.uniprot.org/citations/22340591 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/22340591 |
http://purl.uniprot.org/uniprot/#_A0A0A6YVW7-mappedCitation-22340591 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22340591 |
http://purl.uniprot.org/uniprot/#_A0A0A6YVX7-mappedCitation-22340591 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22340591 |
http://purl.uniprot.org/uniprot/#_A0A0A6YWC4-mappedCitation-22340591 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22340591 |