| http://purl.uniprot.org/citations/22392991 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/22392991 | http://www.w3.org/2000/01/rdf-schema#comment | "Endoreduplication is the process where a cell replicates its genome without mitosis and cytokinesis, often followed by cell differentiation. This alternative cell cycle results in various levels of endoploidy, reaching 4× or higher one haploid set of chromosomes. Endoreduplication is found in animals and is widespread in plants, where it plays a major role in cellular differentiation and plant development. Here, we show that variation in endoreduplication between Arabidopsis thaliana accessions Columbia-0 and Kashmir is controlled by two major quantitative trait loci, ENDO-1 and ENDO-2. A local candidate gene association analysis in a set of 87 accessions, combined with expression analysis, identified CYCD5;1 as the most likely candidate gene underlying ENDO-2, operating as a rate-determining factor of endoreduplication. In accordance, both the overexpression and silencing of CYCD5;1 were effective in changing DNA ploidy levels, confirming CYCD5;1 to be a previously undescribed quantitative trait gene underlying endoreduplication in Arabidopsis."xsd:string |
| http://purl.uniprot.org/citations/22392991 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.1120811109"xsd:string |
| http://purl.uniprot.org/citations/22392991 | http://purl.uniprot.org/core/author | "Inze D."xsd:string |
| http://purl.uniprot.org/citations/22392991 | http://purl.uniprot.org/core/author | "Russinova E."xsd:string |
| http://purl.uniprot.org/citations/22392991 | http://purl.uniprot.org/core/author | "Zhang F."xsd:string |
| http://purl.uniprot.org/citations/22392991 | http://purl.uniprot.org/core/author | "Vuylsteke M."xsd:string |
| http://purl.uniprot.org/citations/22392991 | http://purl.uniprot.org/core/author | "De Veylder L."xsd:string |
| http://purl.uniprot.org/citations/22392991 | http://purl.uniprot.org/core/author | "De Smet L."xsd:string |
| http://purl.uniprot.org/citations/22392991 | http://purl.uniprot.org/core/author | "Dhondt S."xsd:string |
| http://purl.uniprot.org/citations/22392991 | http://purl.uniprot.org/core/author | "Vercauteren I."xsd:string |
| http://purl.uniprot.org/citations/22392991 | http://purl.uniprot.org/core/author | "Boruc J."xsd:string |
| http://purl.uniprot.org/citations/22392991 | http://purl.uniprot.org/core/author | "Sterken R."xsd:string |
| http://purl.uniprot.org/citations/22392991 | http://purl.uniprot.org/core/author | "Vercauteren A."xsd:string |
| http://purl.uniprot.org/citations/22392991 | http://purl.uniprot.org/core/author | "Kiekens R."xsd:string |
| http://purl.uniprot.org/citations/22392991 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
| http://purl.uniprot.org/citations/22392991 | http://purl.uniprot.org/core/name | "Proc Natl Acad Sci U S A"xsd:string |
| http://purl.uniprot.org/citations/22392991 | http://purl.uniprot.org/core/pages | "4678-4683"xsd:string |
| http://purl.uniprot.org/citations/22392991 | http://purl.uniprot.org/core/title | "Combined linkage and association mapping reveals CYCD5;1 as a quantitative trait gene for endoreduplication in Arabidopsis."xsd:string |
| http://purl.uniprot.org/citations/22392991 | http://purl.uniprot.org/core/volume | "109"xsd:string |
| http://purl.uniprot.org/citations/22392991 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/22392991 |
| http://purl.uniprot.org/citations/22392991 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/22392991 |
| http://purl.uniprot.org/uniprot/Q2V3B2#attribution-EFA295C37CAE890258198E589DDABBBF | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/22392991 |
| http://purl.uniprot.org/uniprot/#_A0A2H1ZEQ4-mappedCitation-22392991 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22392991 |
| http://purl.uniprot.org/uniprot/#_A0A178UUR3-mappedCitation-22392991 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22392991 |