| http://purl.uniprot.org/citations/22431976 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/22431976 | http://www.w3.org/2000/01/rdf-schema#comment | "Early steps of eukaryotic ribosome biogenesis require a large set of ribosome biogenesis factors which transiently interact with nascent rRNA precursors (pre-rRNA). Most likely, concomitant with that initial contacts between ribosomal proteins (r-proteins) and ribosome precursors (pre-ribosomes) are established which are converted into robust interactions between pre-rRNA and r-proteins during the course of ribosome maturation. Here we analysed the interrelationship between r-protein assembly events and the transient interactions of ribosome biogenesis factors with early pre-ribosomal intermediates termed 90S pre-ribosomes or small ribosomal subunit (SSU) processome in yeast cells. We observed that components of the SSU processome UTP-A and UTP-B sub-modules were recruited to early pre-ribosomes independently of all tested r-proteins. On the other hand, groups of SSU processome components were identified whose association with early pre-ribosomes was affected by specific r-protein assembly events in the head-platform interface of the SSU. One of these components, Noc4p, appeared to be itself required for robust incorporation of r-proteins into the SSU head domain. Altogether, the data reveal an emerging network of specific interrelationships between local r-protein assembly events and the functional interactions of SSU processome components with early pre-ribosomes. They point towards some of these components being transient primary pre-rRNA in vivo binders and towards a role for others in coordinating the assembly of major SSU domains."xsd:string |
| http://purl.uniprot.org/citations/22431976 | http://purl.org/dc/terms/identifier | "doi:10.1371/journal.pone.0032552"xsd:string |
| http://purl.uniprot.org/citations/22431976 | http://purl.uniprot.org/core/author | "Deutzmann R."xsd:string |
| http://purl.uniprot.org/citations/22431976 | http://purl.uniprot.org/core/author | "Hochmuth E."xsd:string |
| http://purl.uniprot.org/citations/22431976 | http://purl.uniprot.org/core/author | "Tschochner H."xsd:string |
| http://purl.uniprot.org/citations/22431976 | http://purl.uniprot.org/core/author | "Perez-Fernandez J."xsd:string |
| http://purl.uniprot.org/citations/22431976 | http://purl.uniprot.org/core/author | "Griesenbeck J."xsd:string |
| http://purl.uniprot.org/citations/22431976 | http://purl.uniprot.org/core/author | "Milkereit P."xsd:string |
| http://purl.uniprot.org/citations/22431976 | http://purl.uniprot.org/core/author | "Hierlmeier T."xsd:string |
| http://purl.uniprot.org/citations/22431976 | http://purl.uniprot.org/core/author | "Ohmayer U."xsd:string |
| http://purl.uniprot.org/citations/22431976 | http://purl.uniprot.org/core/author | "Jakob S."xsd:string |
| http://purl.uniprot.org/citations/22431976 | http://purl.uniprot.org/core/author | "Neueder A."xsd:string |
| http://purl.uniprot.org/citations/22431976 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
| http://purl.uniprot.org/citations/22431976 | http://purl.uniprot.org/core/name | "PLoS One"xsd:string |
| http://purl.uniprot.org/citations/22431976 | http://purl.uniprot.org/core/pages | "e32552"xsd:string |
| http://purl.uniprot.org/citations/22431976 | http://purl.uniprot.org/core/title | "Interrelationships between yeast ribosomal protein assembly events and transient ribosome biogenesis factors interactions in early pre-ribosomes."xsd:string |
| http://purl.uniprot.org/citations/22431976 | http://purl.uniprot.org/core/volume | "7"xsd:string |
| http://purl.uniprot.org/citations/22431976 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/22431976 |
| http://purl.uniprot.org/citations/22431976 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/22431976 |
| http://purl.uniprot.org/uniprot/#_P0C0W1-mappedCitation-22431976 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22431976 |
| http://purl.uniprot.org/uniprot/#_P39516-mappedCitation-22431976 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22431976 |
| http://purl.uniprot.org/uniprot/#_P06367-mappedCitation-22431976 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22431976 |
| http://purl.uniprot.org/uniprot/#_P0CX47-mappedCitation-22431976 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22431976 |
| http://purl.uniprot.org/uniprot/#_P0CX48-mappedCitation-22431976 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22431976 |