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| http://purl.uniprot.org/citations/22438833 | http://www.w3.org/2000/01/rdf-schema#comment | "Insects utilize diverse families of ion channels to respond to environmental cues and control mating, feeding, and the response to threats. Although degenerin/epithelial sodium channels (DEG/ENaC) represent one of the largest families of ion channels in Drosophila melanogaster, the physiological functions of these proteins are still poorly understood. We found that the DEG/ENaC channel ppk23 is expressed in a subpopulation of sexually dimorphic gustatory-like chemosensory bristles that are distinct from those expressing feeding-related gustatory receptors. Disrupting ppk23 or inhibiting activity of ppk23-expressing neurons did not alter gustatory responses. Instead, blocking ppk23-positive neurons or mutating the ppk23 gene delayed the initiation and reduced the intensity of male courtship. Furthermore, mutations in ppk23 altered the behavioral response of males to the female-specific aphrodisiac pheromone 7(Z), 11(Z)-Heptacosadiene. Together, these data indicate that ppk23 and the cells expressing it play an important role in the peripheral sensory system that determines sexual behavior in Drosophila."xsd:string |
| http://purl.uniprot.org/citations/22438833 | http://purl.org/dc/terms/identifier | "doi:10.1371/journal.pgen.1002587"xsd:string |
| http://purl.uniprot.org/citations/22438833 | http://purl.uniprot.org/core/author | "Sun Y."xsd:string |
| http://purl.uniprot.org/citations/22438833 | http://purl.uniprot.org/core/author | "Lu B."xsd:string |
| http://purl.uniprot.org/citations/22438833 | http://purl.uniprot.org/core/author | "Welsh M.J."xsd:string |
| http://purl.uniprot.org/citations/22438833 | http://purl.uniprot.org/core/author | "Ben-Shahar Y."xsd:string |
| http://purl.uniprot.org/citations/22438833 | http://purl.uniprot.org/core/author | "LaMora A."xsd:string |
| http://purl.uniprot.org/citations/22438833 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
| http://purl.uniprot.org/citations/22438833 | http://purl.uniprot.org/core/name | "PLoS Genet"xsd:string |
| http://purl.uniprot.org/citations/22438833 | http://purl.uniprot.org/core/pages | "e1002587"xsd:string |
| http://purl.uniprot.org/citations/22438833 | http://purl.uniprot.org/core/title | "ppk23-Dependent chemosensory functions contribute to courtship behavior in Drosophila melanogaster."xsd:string |
| http://purl.uniprot.org/citations/22438833 | http://purl.uniprot.org/core/volume | "8"xsd:string |
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