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http://purl.uniprot.org/citations/22446944http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/22446944http://www.w3.org/2000/01/rdf-schema#comment"Translocation renal cell carcinoma is a newly recognized subtype of renal cell carcinoma (RCC) with chromosomal translocations involving TFE3 (Xp11.2) or, less frequently, TFEB (6p21). Xp11 translocation RCC was originally described as a pediatric neoplasm representing 20% to 40% of pediatric RCCs, with a much lower frequency in the adult population. TFEB translocation RCC is very rare, with approximately 10 cases reported in the literature. Here, we describe the clinicopathologic features of adult translocation RCC from a single institution. Using tissue microarray, immunohistochemistry, cytogenetic examination, and fluorescence in situ hybridization, we identified 6 (∼5%) cases of TFE3 translocation RCC and 1 (<1%) case of TFEB translocation RCC in 121 consecutive adult RCC cases between 2001 and 2009. Our results suggest that weak TFE3 staining of a significant proportion of RCC cases may be because of expression of the full-length TFE3 protein rather than the chimeric fusion protein resulting from chromosomal translocation."xsd:string
http://purl.uniprot.org/citations/22446944http://purl.org/dc/terms/identifier"doi:10.1097/pas.0b013e31824f24a6"xsd:string
http://purl.uniprot.org/citations/22446944http://purl.uniprot.org/core/author"Yang Y."xsd:string
http://purl.uniprot.org/citations/22446944http://purl.uniprot.org/core/author"Zhong M."xsd:string
http://purl.uniprot.org/citations/22446944http://purl.uniprot.org/core/author"Linehan W.M."xsd:string
http://purl.uniprot.org/citations/22446944http://purl.uniprot.org/core/author"Cai D."xsd:string
http://purl.uniprot.org/citations/22446944http://purl.uniprot.org/core/author"Cordon-Cardo C."xsd:string
http://purl.uniprot.org/citations/22446944http://purl.uniprot.org/core/author"Merino M.J."xsd:string
http://purl.uniprot.org/citations/22446944http://purl.uniprot.org/core/author"Osborne L."xsd:string
http://purl.uniprot.org/citations/22446944http://purl.uniprot.org/core/author"Paniz-Mondolfi A.E."xsd:string
http://purl.uniprot.org/citations/22446944http://purl.uniprot.org/core/author"Geller M."xsd:string
http://purl.uniprot.org/citations/22446944http://purl.uniprot.org/core/author"De Angelo P."xsd:string
http://purl.uniprot.org/citations/22446944http://purl.uniprot.org/core/date"2012"xsd:gYear
http://purl.uniprot.org/citations/22446944http://purl.uniprot.org/core/name"Am J Surg Pathol"xsd:string
http://purl.uniprot.org/citations/22446944http://purl.uniprot.org/core/pages"654-662"xsd:string
http://purl.uniprot.org/citations/22446944http://purl.uniprot.org/core/title"Translocation renal cell carcinomas in adults: a single-institution experience."xsd:string
http://purl.uniprot.org/citations/22446944http://purl.uniprot.org/core/volume"36"xsd:string
http://purl.uniprot.org/citations/22446944http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/22446944
http://purl.uniprot.org/citations/22446944http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/22446944
http://purl.uniprot.org/uniprot/#_B0QYS6-mappedCitation-22446944http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/22446944
http://purl.uniprot.org/uniprot/#_B4DIA5-mappedCitation-22446944http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/22446944
http://purl.uniprot.org/uniprot/#_B1AKB4-mappedCitation-22446944http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/22446944
http://purl.uniprot.org/uniprot/#_B1AKB5-mappedCitation-22446944http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/22446944
http://purl.uniprot.org/uniprot/#_B4DPL3-mappedCitation-22446944http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/22446944