| http://purl.uniprot.org/citations/22500989 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/22500989 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/22500989 | http://www.w3.org/2000/01/rdf-schema#comment | "WD repeat-containing protein 42A (WDR42A) is a member of the WD40-repeat proteins. Here, we investigated the localization pattern of WDR42A in living cells. By mutational analysis, a nuclear localization signal, 114PRRRVQRKR122, was for the first time determined. The dominant negative, co-immunoprecipitation and GST pull-down results further demonstrated that the nuclear import of WDR42A was mediated by karyopherin-α1/β1 in conjunction with the GTPase Ran. Additionally, a nuclear export signal, 39IEVEASDLSLSL50, was verified to be a functional NES, which mediated the nuclear export through Chromosome Region Maintenance 1 dependent pathway. All these data suggest WDR42A is a nucleocytoplasmic shuttling protein."xsd:string |
| http://purl.uniprot.org/citations/22500989 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2012.02.053"xsd:string |
| http://purl.uniprot.org/citations/22500989 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2012.02.053"xsd:string |
| http://purl.uniprot.org/citations/22500989 | http://purl.uniprot.org/core/author | "Li M."xsd:string |
| http://purl.uniprot.org/citations/22500989 | http://purl.uniprot.org/core/author | "Li M."xsd:string |
| http://purl.uniprot.org/citations/22500989 | http://purl.uniprot.org/core/author | "Wang S."xsd:string |
| http://purl.uniprot.org/citations/22500989 | http://purl.uniprot.org/core/author | "Wang S."xsd:string |
| http://purl.uniprot.org/citations/22500989 | http://purl.uniprot.org/core/author | "Wu F."xsd:string |
| http://purl.uniprot.org/citations/22500989 | http://purl.uniprot.org/core/author | "Wu F."xsd:string |
| http://purl.uniprot.org/citations/22500989 | http://purl.uniprot.org/core/author | "Zheng C."xsd:string |
| http://purl.uniprot.org/citations/22500989 | http://purl.uniprot.org/core/author | "Zheng C."xsd:string |
| http://purl.uniprot.org/citations/22500989 | http://purl.uniprot.org/core/author | "Xing J."xsd:string |
| http://purl.uniprot.org/citations/22500989 | http://purl.uniprot.org/core/author | "Xing J."xsd:string |
| http://purl.uniprot.org/citations/22500989 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
| http://purl.uniprot.org/citations/22500989 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
| http://purl.uniprot.org/citations/22500989 | http://purl.uniprot.org/core/name | "FEBS Lett."xsd:string |
| http://purl.uniprot.org/citations/22500989 | http://purl.uniprot.org/core/name | "FEBS Lett."xsd:string |
| http://purl.uniprot.org/citations/22500989 | http://purl.uniprot.org/core/pages | "1079-1085"xsd:string |
| http://purl.uniprot.org/citations/22500989 | http://purl.uniprot.org/core/pages | "1079-1085"xsd:string |
| http://purl.uniprot.org/citations/22500989 | http://purl.uniprot.org/core/title | "Characterization of nuclear import and export signals determining the subcellular localization of WD repeat-containing protein 42A (WDR42A)."xsd:string |
| http://purl.uniprot.org/citations/22500989 | http://purl.uniprot.org/core/title | "Characterization of nuclear import and export signals determining the subcellular localization of WD repeat-containing protein 42A (WDR42A)."xsd:string |
| http://purl.uniprot.org/citations/22500989 | http://purl.uniprot.org/core/volume | "586"xsd:string |
| http://purl.uniprot.org/citations/22500989 | http://purl.uniprot.org/core/volume | "586"xsd:string |