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http://purl.uniprot.org/citations/22538654http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/22538654http://www.w3.org/2000/01/rdf-schema#comment"Replacement of glycine 227 in the fifth WD40 motif of α-COP/Ret1p/Soo1p by charged or aromatic amino acids is responsible for the temperature-dependent osmo-sensitivity of Saccharomyces cerevisiae, while truncations of WD40 motifs exerted a reduction in cell growth rate and impairment in assembly of cell-wall associated proteins such as enolase and Gas1p. Yeast two-hybrid analysis revealed that the ret1-1/soo1-1 mutation of α-COP abolished the interaction with β- and ɛ-COP, respectively, and that the interaction between α-COP and β-COP relied on the WD40 domain of α-COP. Furthermore, although the WD40 domain is dispensable for interaction of α-COP with ɛ-COP, structural alterations in the WD40 domain could impair the interaction."xsd:string
http://purl.uniprot.org/citations/22538654http://purl.org/dc/terms/identifier"doi:10.1007/s12275-012-1326-z"xsd:string
http://purl.uniprot.org/citations/22538654http://purl.uniprot.org/core/author"Kim K.H."xsd:string
http://purl.uniprot.org/citations/22538654http://purl.uniprot.org/core/author"Park Y.H."xsd:string
http://purl.uniprot.org/citations/22538654http://purl.uniprot.org/core/author"Park H.M."xsd:string
http://purl.uniprot.org/citations/22538654http://purl.uniprot.org/core/author"Jeong K.Y."xsd:string
http://purl.uniprot.org/citations/22538654http://purl.uniprot.org/core/author"Kim E.K."xsd:string
http://purl.uniprot.org/citations/22538654http://purl.uniprot.org/core/date"2012"xsd:gYear
http://purl.uniprot.org/citations/22538654http://purl.uniprot.org/core/name"J Microbiol"xsd:string
http://purl.uniprot.org/citations/22538654http://purl.uniprot.org/core/pages"256-262"xsd:string
http://purl.uniprot.org/citations/22538654http://purl.uniprot.org/core/title"Effects of mutations in the WD40 domain of alpha-COP on its interaction with the COPI coatomer in Saccharomyces cerevisiae."xsd:string
http://purl.uniprot.org/citations/22538654http://purl.uniprot.org/core/volume"50"xsd:string
http://purl.uniprot.org/citations/22538654http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/22538654
http://purl.uniprot.org/citations/22538654http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/22538654
http://purl.uniprot.org/uniprot/#_P53622-mappedCitation-22538654http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/22538654
http://purl.uniprot.org/uniprot/P53622http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/22538654