| http://purl.uniprot.org/citations/22582013 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/22582013 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/22582013 | http://www.w3.org/2000/01/rdf-schema#comment | "Protein phosphorylation is a fundamental mechanism regulating nearly every aspect of cellular life. Several secreted proteins are phosphorylated, but the kinases responsible are unknown. We identified a family of atypical protein kinases that localize within the Golgi apparatus and are secreted. Fam20C appears to be the Golgi casein kinase that phosphorylates secretory pathway proteins within S-x-E motifs. Fam20C phosphorylates the caseins and several secreted proteins implicated in biomineralization, including the small integrin-binding ligand, N-linked glycoproteins (SIBLINGs). Consequently, mutations in Fam20C cause an osteosclerotic bone dysplasia in humans known as Raine syndrome. Fam20C is thus a protein kinase dedicated to the phosphorylation of extracellular proteins."xsd:string |
| http://purl.uniprot.org/citations/22582013 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1217817"xsd:string |
| http://purl.uniprot.org/citations/22582013 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1217817"xsd:string |
| http://purl.uniprot.org/citations/22582013 | http://purl.uniprot.org/core/author | "Grishin N.V."xsd:string |
| http://purl.uniprot.org/citations/22582013 | http://purl.uniprot.org/core/author | "Grishin N.V."xsd:string |
| http://purl.uniprot.org/citations/22582013 | http://purl.uniprot.org/core/author | "Xiao J."xsd:string |
| http://purl.uniprot.org/citations/22582013 | http://purl.uniprot.org/core/author | "Xiao J."xsd:string |
| http://purl.uniprot.org/citations/22582013 | http://purl.uniprot.org/core/author | "Kinch L.N."xsd:string |
| http://purl.uniprot.org/citations/22582013 | http://purl.uniprot.org/core/author | "Kinch L.N."xsd:string |
| http://purl.uniprot.org/citations/22582013 | http://purl.uniprot.org/core/author | "Dixon J.E."xsd:string |
| http://purl.uniprot.org/citations/22582013 | http://purl.uniprot.org/core/author | "Dixon J.E."xsd:string |
| http://purl.uniprot.org/citations/22582013 | http://purl.uniprot.org/core/author | "Wen J."xsd:string |
| http://purl.uniprot.org/citations/22582013 | http://purl.uniprot.org/core/author | "Wen J."xsd:string |
| http://purl.uniprot.org/citations/22582013 | http://purl.uniprot.org/core/author | "Engel J.L."xsd:string |
| http://purl.uniprot.org/citations/22582013 | http://purl.uniprot.org/core/author | "Engel J.L."xsd:string |
| http://purl.uniprot.org/citations/22582013 | http://purl.uniprot.org/core/author | "Tagliabracci V.S."xsd:string |
| http://purl.uniprot.org/citations/22582013 | http://purl.uniprot.org/core/author | "Tagliabracci V.S."xsd:string |
| http://purl.uniprot.org/citations/22582013 | http://purl.uniprot.org/core/author | "Wiley S.E."xsd:string |
| http://purl.uniprot.org/citations/22582013 | http://purl.uniprot.org/core/author | "Wiley S.E."xsd:string |
| http://purl.uniprot.org/citations/22582013 | http://purl.uniprot.org/core/author | "Worby C.A."xsd:string |
| http://purl.uniprot.org/citations/22582013 | http://purl.uniprot.org/core/author | "Worby C.A."xsd:string |
| http://purl.uniprot.org/citations/22582013 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
| http://purl.uniprot.org/citations/22582013 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |