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http://purl.uniprot.org/citations/2260977http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/2260977http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/2260977http://www.w3.org/2000/01/rdf-schema#comment"In the amphibian pars intermedia, secretion of proopiomelanocortin (POMC)-derived peptides is controlled by multiple factors including classical neurotransmitters and neuropeptides. To pursue questions concerning the regulation of POMC gene expression in Rana ridibunda, we have isolated and characterized a full-length cDNA for frog POMC. A cDNA clone isolated from a frog pituitary library contains an open-reading frame of 780-bp that predicts a 260 amino acid POMC protein. The structure of frog POMC demonstrates considerable amino acid sequence similarity with POMC from other species. In particular, the sequence of alpha-melanotropin (alpha-MSH) is identical in frog and all mammalian species studied so far, while adrenocorticotropin (ACTH) and beta-endorphin exhibit 79% and 84% homology with their human counterpart. Frog POMC contains only one potential asparagine-linked N-glycosylation signal (Asn-Ser-Thr) within the gamma-MSH domain. The alpha-MSH sequence is C-terminally flanked by the Gly-Lys-Lys amidation signal while the joining peptide is not amidate."xsd:string
http://purl.uniprot.org/citations/2260977http://purl.org/dc/terms/identifier"doi:10.1016/s0006-291x(05)80085-3"xsd:string
http://purl.uniprot.org/citations/2260977http://purl.org/dc/terms/identifier"doi:10.1016/s0006-291x(05)80085-3"xsd:string
http://purl.uniprot.org/citations/2260977http://purl.uniprot.org/core/author"Hilario E."xsd:string
http://purl.uniprot.org/citations/2260977http://purl.uniprot.org/core/author"Hilario E."xsd:string
http://purl.uniprot.org/citations/2260977http://purl.uniprot.org/core/author"Vaudry H."xsd:string
http://purl.uniprot.org/citations/2260977http://purl.uniprot.org/core/author"Vaudry H."xsd:string
http://purl.uniprot.org/citations/2260977http://purl.uniprot.org/core/author"Lihrmann I."xsd:string
http://purl.uniprot.org/citations/2260977http://purl.uniprot.org/core/author"Lihrmann I."xsd:string
http://purl.uniprot.org/citations/2260977http://purl.uniprot.org/core/date"1990"xsd:gYear
http://purl.uniprot.org/citations/2260977http://purl.uniprot.org/core/date"1990"xsd:gYear
http://purl.uniprot.org/citations/2260977http://purl.uniprot.org/core/name"Biochem. Biophys. Res. Commun."xsd:string
http://purl.uniprot.org/citations/2260977http://purl.uniprot.org/core/name"Biochem. Biophys. Res. Commun."xsd:string
http://purl.uniprot.org/citations/2260977http://purl.uniprot.org/core/pages"653-659"xsd:string
http://purl.uniprot.org/citations/2260977http://purl.uniprot.org/core/pages"653-659"xsd:string
http://purl.uniprot.org/citations/2260977http://purl.uniprot.org/core/title"Characterization of the cDNA encoding proopiomelanocortin in the frog Rana ridibunda."xsd:string
http://purl.uniprot.org/citations/2260977http://purl.uniprot.org/core/title"Characterization of the cDNA encoding proopiomelanocortin in the frog Rana ridibunda."xsd:string
http://purl.uniprot.org/citations/2260977http://purl.uniprot.org/core/volume"173"xsd:string
http://purl.uniprot.org/citations/2260977http://purl.uniprot.org/core/volume"173"xsd:string
http://purl.uniprot.org/citations/2260977http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/2260977
http://purl.uniprot.org/citations/2260977http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/2260977
http://purl.uniprot.org/citations/2260977http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/2260977
http://purl.uniprot.org/citations/2260977http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/2260977