| http://purl.uniprot.org/citations/22621902 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/22621902 | http://www.w3.org/2000/01/rdf-schema#comment | "In Saccharomyces cerevisiae, the transcriptional program triggered by cell wall stress is coordinated by Slt2/Mpk1, the mitogen-activated protein kinase (MAPK) of the cell wall integrity (CWI) pathway, and is mostly mediated by the transcription factor Rlm1. Here we show that the SWI/SNF chromatin-remodeling complex plays a critical role in orchestrating the transcriptional response regulated by Rlm1. swi/snf mutants show drastically reduced expression of cell wall stress-responsive genes and hypersensitivity to cell wall-interfering compounds. On stress, binding of RNA Pol II to the promoters of these genes depends on Rlm1, Slt2, and SWI/SNF. Rlm1 physically interacts with SWI/SNF to direct its association to target promoters. Finally, we observe nucleosome displacement at the CWI-responsive gene MLP1/KDX1, which relies on the SWI/SNF complex. Taken together, our results identify the SWI/SNF complex as a key element of the CWI MAPK pathway that mediates the chromatin remodeling necessary for adequate transcriptional response to cell wall stress."xsd:string |
| http://purl.uniprot.org/citations/22621902 | http://purl.org/dc/terms/identifier | "doi:10.1091/mbc.e12-04-0278"xsd:string |
| http://purl.uniprot.org/citations/22621902 | http://purl.uniprot.org/core/author | "Peterson C.L."xsd:string |
| http://purl.uniprot.org/citations/22621902 | http://purl.uniprot.org/core/author | "Arroyo J."xsd:string |
| http://purl.uniprot.org/citations/22621902 | http://purl.uniprot.org/core/author | "Nombela C."xsd:string |
| http://purl.uniprot.org/citations/22621902 | http://purl.uniprot.org/core/author | "Rodriguez-Pena J.M."xsd:string |
| http://purl.uniprot.org/citations/22621902 | http://purl.uniprot.org/core/author | "Garcia R."xsd:string |
| http://purl.uniprot.org/citations/22621902 | http://purl.uniprot.org/core/author | "Diez-Muniz S."xsd:string |
| http://purl.uniprot.org/citations/22621902 | http://purl.uniprot.org/core/author | "Sanz A.B."xsd:string |
| http://purl.uniprot.org/citations/22621902 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
| http://purl.uniprot.org/citations/22621902 | http://purl.uniprot.org/core/name | "Mol Biol Cell"xsd:string |
| http://purl.uniprot.org/citations/22621902 | http://purl.uniprot.org/core/pages | "2805-2817"xsd:string |
| http://purl.uniprot.org/citations/22621902 | http://purl.uniprot.org/core/title | "Chromatin remodeling by the SWI/SNF complex is essential for transcription mediated by the yeast cell wall integrity MAPK pathway."xsd:string |
| http://purl.uniprot.org/citations/22621902 | http://purl.uniprot.org/core/volume | "23"xsd:string |
| http://purl.uniprot.org/citations/22621902 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/22621902 |
| http://purl.uniprot.org/citations/22621902 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/22621902 |
| http://purl.uniprot.org/uniprot/#_P53628-mappedCitation-22621902 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22621902 |
| http://purl.uniprot.org/uniprot/#_Q12224-mappedCitation-22621902 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22621902 |
| http://purl.uniprot.org/uniprot/#_P18888-mappedCitation-22621902 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22621902 |
| http://purl.uniprot.org/uniprot/#_P22082-mappedCitation-22621902 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22621902 |
| http://purl.uniprot.org/uniprot/#_P09547-mappedCitation-22621902 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22621902 |
| http://purl.uniprot.org/uniprot/#_Q00772-mappedCitation-22621902 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22621902 |
| http://purl.uniprot.org/uniprot/#_Q05777-mappedCitation-22621902 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22621902 |
| http://purl.uniprot.org/uniprot/#_P18480-mappedCitation-22621902 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22621902 |