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http://purl.uniprot.org/citations/22664726http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/22664726http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/22664726http://www.w3.org/2000/01/rdf-schema#comment"Here we report on the identification of a human pluripotent embryonic stem cell (hESC) specific mitochondrial protein that is re-expressed in cancer cells, ATAD3B. ATAD3B belongs to the AAA+ ATPase ATAD3 protein family of mitochondrial proteins specific to multicellular eukaryotes. Using loss- and gain-of-function approaches, we show that ATAD3B associates with the ubiquitous ATAD3A species, negatively regulates the interaction of ATAD3A with matrix nucleoid complexes and contributes to a mitochondria fragmentation phenotype. We conclude that ATAD3B is a negative regulator of ATAD3A and may function as an adaptor of mitochondrial homeostasis and metabolism in hESCs and cancer cells."xsd:string
http://purl.uniprot.org/citations/22664726http://purl.org/dc/terms/identifier"doi:10.1016/j.mito.2012.05.005"xsd:string
http://purl.uniprot.org/citations/22664726http://purl.org/dc/terms/identifier"doi:10.1016/j.mito.2012.05.005"xsd:string
http://purl.uniprot.org/citations/22664726http://purl.uniprot.org/core/author"Gilquin B."xsd:string
http://purl.uniprot.org/citations/22664726http://purl.uniprot.org/core/author"Gilquin B."xsd:string
http://purl.uniprot.org/citations/22664726http://purl.uniprot.org/core/author"Baudier J."xsd:string
http://purl.uniprot.org/citations/22664726http://purl.uniprot.org/core/author"Baudier J."xsd:string
http://purl.uniprot.org/citations/22664726http://purl.uniprot.org/core/author"Bennaceur-Griscelli A."xsd:string
http://purl.uniprot.org/citations/22664726http://purl.uniprot.org/core/author"Bennaceur-Griscelli A."xsd:string
http://purl.uniprot.org/citations/22664726http://purl.uniprot.org/core/author"Feraud O."xsd:string
http://purl.uniprot.org/citations/22664726http://purl.uniprot.org/core/author"Feraud O."xsd:string
http://purl.uniprot.org/citations/22664726http://purl.uniprot.org/core/author"Assard N."xsd:string
http://purl.uniprot.org/citations/22664726http://purl.uniprot.org/core/author"Assard N."xsd:string
http://purl.uniprot.org/citations/22664726http://purl.uniprot.org/core/author"Honnorat J."xsd:string
http://purl.uniprot.org/citations/22664726http://purl.uniprot.org/core/author"Honnorat J."xsd:string
http://purl.uniprot.org/citations/22664726http://purl.uniprot.org/core/author"Hubstenberger A."xsd:string
http://purl.uniprot.org/citations/22664726http://purl.uniprot.org/core/author"Hubstenberger A."xsd:string
http://purl.uniprot.org/citations/22664726http://purl.uniprot.org/core/author"Kieffer-Jacquinot S."xsd:string
http://purl.uniprot.org/citations/22664726http://purl.uniprot.org/core/author"Kieffer-Jacquinot S."xsd:string
http://purl.uniprot.org/citations/22664726http://purl.uniprot.org/core/author"Merle N."xsd:string
http://purl.uniprot.org/citations/22664726http://purl.uniprot.org/core/author"Merle N."xsd:string
http://purl.uniprot.org/citations/22664726http://purl.uniprot.org/core/date"2012"xsd:gYear
http://purl.uniprot.org/citations/22664726http://purl.uniprot.org/core/date"2012"xsd:gYear