| http://purl.uniprot.org/citations/22673513 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/22673513 | http://www.w3.org/2000/01/rdf-schema#comment | "Cellular cholesterol levels are tightly regulated and represent a balance of cholesterol uptake, endogenous synthesis and efflux. Although the classic transcriptional regulations of cholesterol metabolism by liver X receptors (LXRs) have been well studied, the potential effects of LXR-responsive microRNAs (miRNAs) still need to be unveiled. Here, we describe that miR-26, an LXR-suppressed miRNA, inhibits the expression of the ATP-binding cassette transporter A1 (ABCA1) and ADP-ribosylation factor-like 7 (ARL7), two LXR target genes which play critical roles in cholesterol efflux. These findings have not only figured out an alternative mechanism for LXR regulation, but also provided a potential therapeutic target for cholesterol metabolic disorders."xsd:string |
| http://purl.uniprot.org/citations/22673513 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2012.03.068"xsd:string |
| http://purl.uniprot.org/citations/22673513 | http://purl.uniprot.org/core/author | "Chen M."xsd:string |
| http://purl.uniprot.org/citations/22673513 | http://purl.uniprot.org/core/author | "Sun D."xsd:string |
| http://purl.uniprot.org/citations/22673513 | http://purl.uniprot.org/core/author | "Zhang J."xsd:string |
| http://purl.uniprot.org/citations/22673513 | http://purl.uniprot.org/core/author | "Wei W."xsd:string |
| http://purl.uniprot.org/citations/22673513 | http://purl.uniprot.org/core/author | "Zhao X."xsd:string |
| http://purl.uniprot.org/citations/22673513 | http://purl.uniprot.org/core/author | "Xie J."xsd:string |
| http://purl.uniprot.org/citations/22673513 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
| http://purl.uniprot.org/citations/22673513 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
| http://purl.uniprot.org/citations/22673513 | http://purl.uniprot.org/core/pages | "1472-1479"xsd:string |
| http://purl.uniprot.org/citations/22673513 | http://purl.uniprot.org/core/title | "MiR-26 controls LXR-dependent cholesterol efflux by targeting ABCA1 and ARL7."xsd:string |
| http://purl.uniprot.org/citations/22673513 | http://purl.uniprot.org/core/volume | "586"xsd:string |
| http://purl.uniprot.org/citations/22673513 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/22673513 |
| http://purl.uniprot.org/citations/22673513 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/22673513 |
| http://purl.uniprot.org/uniprot/#_P56559-mappedCitation-22673513 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22673513 |
| http://purl.uniprot.org/uniprot/#_A0A140LHK8-mappedCitation-22673513 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22673513 |
| http://purl.uniprot.org/uniprot/#_A0A140LHL9-mappedCitation-22673513 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22673513 |
| http://purl.uniprot.org/uniprot/#_A0A140LHR6-mappedCitation-22673513 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22673513 |
| http://purl.uniprot.org/uniprot/#_A0A140LHY6-mappedCitation-22673513 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22673513 |
| http://purl.uniprot.org/uniprot/#_A0A140LIH8-mappedCitation-22673513 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22673513 |
| http://purl.uniprot.org/uniprot/#_A0A140LJ50-mappedCitation-22673513 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22673513 |
| http://purl.uniprot.org/uniprot/#_A2AGR4-mappedCitation-22673513 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22673513 |
| http://purl.uniprot.org/uniprot/#_Q60644-mappedCitation-22673513 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22673513 |