| http://purl.uniprot.org/citations/22679780 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/22679780 | http://www.w3.org/2000/01/rdf-schema#comment | "It was assumed previously that the mutator phenotype of the hms3 mutant was determined by processes taking place in the D-loop. As a next step, genetic analysis was performed to study the interactions between the hsm3 mutation and mutations of the genes that control the initial steps of the D-loop formation. The mutations of the MMS4 and XRS2 genes, which initiate the double-strand break formation and subsequent repair, were shown to completely block HSM3-dependent UV-induced mutagenesis. Mutations of the RAD51, RAD52, and RAD54 genes, which are also involved in the D-loop formation, only slightly decreased the level of UV-induced mutagenesis in the hsm3 mutant. Similar results were observed for the interaction of hsm3 with the mph1 mutation, which stabilizes the D-loop. In contrast, the shu1 mutation, which destabilizes the D-loop structure, led to an extremely high level of UV-induced mutagenesis and displayed epistatic interactions with the hsm3 mutation. The results made it possible to assume that the hsm3 mutation destabilizes the D-loop, which is a key substrate of both Rad5- and Rad52-dependent postreplicative repair pathways."xsd:string |
| http://purl.uniprot.org/citations/22679780 | http://purl.uniprot.org/core/author | "Fedorova I."xsd:string |
| http://purl.uniprot.org/citations/22679780 | http://purl.uniprot.org/core/author | "Evstukhina T.A."xsd:string |
| http://purl.uniprot.org/citations/22679780 | http://purl.uniprot.org/core/author | "Gracheva L.M."xsd:string |
| http://purl.uniprot.org/citations/22679780 | http://purl.uniprot.org/core/author | "Peshekhonov V.T."xsd:string |
| http://purl.uniprot.org/citations/22679780 | http://purl.uniprot.org/core/author | "Koval'tsova S.V."xsd:string |
| http://purl.uniprot.org/citations/22679780 | http://purl.uniprot.org/core/author | "Chernenkov A.I.u."xsd:string |
| http://purl.uniprot.org/citations/22679780 | http://purl.uniprot.org/core/author | "Fedorov D.V."xsd:string |
| http://purl.uniprot.org/citations/22679780 | http://purl.uniprot.org/core/author | "Korolev V."xsd:string |
| http://purl.uniprot.org/citations/22679780 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
| http://purl.uniprot.org/citations/22679780 | http://purl.uniprot.org/core/name | "Genetika"xsd:string |
| http://purl.uniprot.org/citations/22679780 | http://purl.uniprot.org/core/pages | "333-339"xsd:string |
| http://purl.uniprot.org/citations/22679780 | http://purl.uniprot.org/core/title | "[Interaction of the HSM3 gene with genes initiating homologous recombination repair in yeast Saccharomyces cerevisiae]."xsd:string |
| http://purl.uniprot.org/citations/22679780 | http://purl.uniprot.org/core/volume | "48"xsd:string |
| http://purl.uniprot.org/citations/22679780 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/22679780 |
| http://purl.uniprot.org/citations/22679780 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/22679780 |
| http://purl.uniprot.org/uniprot/#_P38348-mappedCitation-22679780 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/22679780 |
| http://purl.uniprot.org/uniprot/P38348 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/22679780 |